Oncofertility in Gynecologic Malignant Tumors  

作　　者：Masataka Adachi Kouji Banno Iori Kisu Megumi Yanokura Moito Iijima Takashi Takeda Kiyoko Umene Yuya Nogami Eiichiro Tominaga Daisuke Aoki 

机构地区：[1]Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan

出　　处：《Journal of Cancer Therapy》2015年第14期1176-1191,共16页癌症治疗（英文）

摘　　要：Long-term survival is the priority in treatment of patients with malignant tumors. In the field of gynecology, fertility preservation has also recently become an important objective due to improved treatment outcomes and different needs of patients. Methods for fertility preservation include cervical conization, ovarian protection against radiation or chemotherapy for ovarian cancer since the ovary is hypersensitive to cancer therapies, treatment of gynecological cancer during pregnancy, and cryopreservation of oocytes, embryos or ovarian tissue before treatment of malignant tumors. Radical trachelectomy for early cervical cancer and treatment with medroxy progesterone acetate for early endometrial carcinoma are also options for fertility preservation, but the efficacy and risk of recurrence have yet to be fully evaluated. The first childbirth following uterine transplantation was also achieved last year and this success has expanded the potential for pregnancy and delivery among cancer survivors.Long-term survival is the priority in treatment of patients with malignant tumors. In the field of gynecology, fertility preservation has also recently become an important objective due to improved treatment outcomes and different needs of patients. Methods for fertility preservation include cervical conization, ovarian protection against radiation or chemotherapy for ovarian cancer since the ovary is hypersensitive to cancer therapies, treatment of gynecological cancer during pregnancy, and cryopreservation of oocytes, embryos or ovarian tissue before treatment of malignant tumors. Radical trachelectomy for early cervical cancer and treatment with medroxy progesterone acetate for early endometrial carcinoma are also options for fertility preservation, but the efficacy and risk of recurrence have yet to be fully evaluated. The first childbirth following uterine transplantation was also achieved last year and this success has expanded the potential for pregnancy and delivery among cancer survivors.

关 键 词：GYNECOLOGICAL Cancer FERTILITY Preservation CRYOPRESERVATION UTERINE Transplantation Pregnancy 

分 类 号：R73[医药卫生—肿瘤]