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作 者:Yasuhiro Tsukamoto Barry Hendler Stuart Greenberg
机构地区:[1]Department of Animal Sciences, Graduate School of Environmental & Biological Sciences, Kyoto Prefecture University, Kyoto, Japan [2]Microfollicular Hair Transplantation, Ambler, PA, USA [3]Clinical Studies, OstriGen Holdings, West Newton, MA, USA
出 处:《Journal of Cosmetics, Dermatological Sciences and Applications》2018年第4期179-184,共6页化妆品、皮肤病及应用期刊(英文)
摘 要:The hormone dihydrotestosterone (DHT) and the catalyst 5α-reductase play very important roles in the hair loss due to androgenetic alopecia (AGA). Recently, some chemicals against these hormones have been commercialized as therapeutics for AGA. In the present study, we have attempted to find out the potential effects of antibodies on AGA therapeutics as an inhibitor of androgenic hormones. The immune system of the ostrich is believed to be the most versatile and powerful of any animal on the planet, and antibodies derived from the ostrich egg yolk are now being developed for a wide range of diseases and ailments. Ostrich antibodies against DHT and 5α-reductase have been produced and combined with antibodies against harmful skin bacteria to restore normal hair growth in AGA cases. Preliminary testing with six volunteer subjects showed that ostrich antibodies were clearly quite effective in hair regrowth.The hormone dihydrotestosterone (DHT) and the catalyst 5α-reductase play very important roles in the hair loss due to androgenetic alopecia (AGA). Recently, some chemicals against these hormones have been commercialized as therapeutics for AGA. In the present study, we have attempted to find out the potential effects of antibodies on AGA therapeutics as an inhibitor of androgenic hormones. The immune system of the ostrich is believed to be the most versatile and powerful of any animal on the planet, and antibodies derived from the ostrich egg yolk are now being developed for a wide range of diseases and ailments. Ostrich antibodies against DHT and 5α-reductase have been produced and combined with antibodies against harmful skin bacteria to restore normal hair growth in AGA cases. Preliminary testing with six volunteer subjects showed that ostrich antibodies were clearly quite effective in hair regrowth.
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