Serum Lipids and Lipokines as Prognostic/Diagnostic Biomarkers in Common Cancers  

作　　者：Nikolaos Dogkas Maria Τrapali Christine Fountzoula Georgios Albert Karikas Petros Karkalousos Nikolaos Dogkas;Maria Τrapali;Christine Fountzoula;Georgios Albert Karikas;Petros Karkalousos(Biochemistry Laboratory, General Anticancer Hospital of Piraeus “METAXA”, Piraeus, Greece;Department of Biomedical Sciences, School of Health and Care Sciences, University of West Attica, Athens, Greece)

机构地区：[1]Biochemistry Laboratory, General Anticancer Hospital of Piraeus “METAXA”, Piraeus, Greece [2]Department of Biomedical Sciences, School of Health and Care Sciences, University of West Attica, Athens, Greece

出　　处：《Journal of Diabetes Mellitus》2022年第2期122-140,共19页糖尿病（英文）

摘　　要：Total cholesterol (CHOL) levels have been shown in many studies, to be higher in people with several types of cancer. Similar results are observed for both triglycerides (TG) and low-density cholesterol (LDL), as opposed to high-density cholesterol (HDL). Chemotherapy seems to reduce CHOL and LDL, leading to a reduction. Furthermore, the recurrence of high levels of CHOL, TG and LDL, as well as low levels of HDL, after receiving treatment, or when patients appear to have been cured, are signs of a possible recurrence of the disease. Lipoprotein α (Lpa), occurs at higher levels in patients than in healthy people, whereas lipokines resistin and bisfatin, “hormonal” products of adipose tissue exhibited high levels in cancer cases, compared to control groups.Total cholesterol (CHOL) levels have been shown in many studies, to be higher in people with several types of cancer. Similar results are observed for both triglycerides (TG) and low-density cholesterol (LDL), as opposed to high-density cholesterol (HDL). Chemotherapy seems to reduce CHOL and LDL, leading to a reduction. Furthermore, the recurrence of high levels of CHOL, TG and LDL, as well as low levels of HDL, after receiving treatment, or when patients appear to have been cured, are signs of a possible recurrence of the disease. Lipoprotein α (Lpa), occurs at higher levels in patients than in healthy people, whereas lipokines resistin and bisfatin, “hormonal” products of adipose tissue exhibited high levels in cancer cases, compared to control groups.

关 键 词：Cancer Total Cholesterol TRIGLYCERIDES HDL LDL RESISTIN VISFATIN 

分 类 号：R73[医药卫生—肿瘤]