Vitamin D: Level of Vitamin D3 in AFB Positive PTB Patients in Initial Diagnostic Phase  

作　　者：Anwar Ali Jamali Jawaid Hussain Lighari Shamasddin Shaikh Ghulam Mustafa Jamali Bhojo Mal Tanwani Muhammad Aslam Channa Ameer Ali Jamali Muhammad Ali Suhail 

机构地区：[1]Department of Medicine, Peoples University of Medical and Health Sciences, Nawabshah, Pakistan [2]Department of Community Medicine, Peoples University of Medical and Health Sciences, Nawabshah, Pakistan [3]Department of Physiology, Peoples University of Medical and Health Sciences for Women, Nawabshah, Pakistan [4]Department of Anatomy, Gambat Institute of Medical Sciences, Khairpur, Pakistan [5]Department of Peadiatrics, Peoples University of Medical and Health Sciences for Women, Nawabshah, Pakistan [6]Department of Surgery, Peoples University of Medical and Health Sciences for Women, Nawabshah, Pakistan

出　　处：《Journal of Tuberculosis Research》2018年第4期251-269,共19页结核病研究（英文）

摘　　要：Background: A relationship among vitamin D and pulmonary tuberculosis. Objective: To conclude the occurrence of Vitamin D insufficiency in subjects suffering from pulmonary TB. Design: This was a cross sectional study. Setting: Current study was performed at department of medicine, Peoples Medical College Hospital Nawabshah starting from January 2017 to December 2017. Samples: 385 AFB positive subjects of pulmonary tuberculosis after achieving the criteria of selection were recruited. Material and Methods: After a brief discussion, the patients were characterized for variable evaluation such as age, gender, sputum AFB and duration of disease and presence of low vitamin D levels. Sputum AFB criterion was used for Data collection. Fasting blood samples were collected for analysis of vitamin D levels in all subjects of AFB positive pulmonary tuberculosis. Results: In 385 diagnosed patients with smear positive PTB, 273 (70.9%) males and 112 (29.1%) were female. Vitamin D levels were within normal or sufficient range in 134 (34.8%), below normal range in 251 (65.2%) cases (insufficient in 09.56% (24/251) and deficient in 90.43% (227/251) cases). Conclusion: Decreased levels of vitamin D were common in subjects with AFB smear Positive PTB cases.Background: A relationship among vitamin D and pulmonary tuberculosis. Objective: To conclude the occurrence of Vitamin D insufficiency in subjects suffering from pulmonary TB. Design: This was a cross sectional study. Setting: Current study was performed at department of medicine, Peoples Medical College Hospital Nawabshah starting from January 2017 to December 2017. Samples: 385 AFB positive subjects of pulmonary tuberculosis after achieving the criteria of selection were recruited. Material and Methods: After a brief discussion, the patients were characterized for variable evaluation such as age, gender, sputum AFB and duration of disease and presence of low vitamin D levels. Sputum AFB criterion was used for Data collection. Fasting blood samples were collected for analysis of vitamin D levels in all subjects of AFB positive pulmonary tuberculosis. Results: In 385 diagnosed patients with smear positive PTB, 273 (70.9%) males and 112 (29.1%) were female. Vitamin D levels were within normal or sufficient range in 134 (34.8%), below normal range in 251 (65.2%) cases (insufficient in 09.56% (24/251) and deficient in 90.43% (227/251) cases). Conclusion: Decreased levels of vitamin D were common in subjects with AFB smear Positive PTB cases.

关 键 词：PULMONARY TUBERCULOSIS VITAMIN D VITAMIN D INSUFFICIENCY 25-Hydroxyvitamin D 

分 类 号：R5[医药卫生—内科学]