From Russia with Polyuria  

作　　者：DaLim Ki Udaya M. Kabadi 

机构地区：[1]Des Moines University, Des Moines, Iowa, USA [2]Veterans Affairs Medical Center, Des Moines, Iowa, USA [3]University of Iowa, Iowa City, Iowa, USA

出　　处：《Open Journal of Endocrine and Metabolic Diseases》2015年第5期51-53,共3页内分泌与新陈代谢疾病期刊（英文）

摘　　要：Introduction: Polyuria is a sign for many disease processes, including diabetes mellitus and diabetes insipidus. Urine osmolarity helps distinguish osmotic diuresis caused by diabetes mellitus from water dieresis induced by diabetes insipidus. Case Presentation: We report a case of a 48-year-old woman who presented with polyuria, polydipsia, nocturia, and weight loss after a return from a visit to Russia, during which she received a five-day course of antibiotic Demeclocycline, a tetracycline derivative for dental treatment. She recovered from all clinical manifestations by 8 weeks. Conclusion: Manifestation of transient nephrogenic diabetes insipidus is induced by Demeclocycline.Introduction: Polyuria is a sign for many disease processes, including diabetes mellitus and diabetes insipidus. Urine osmolarity helps distinguish osmotic diuresis caused by diabetes mellitus from water dieresis induced by diabetes insipidus. Case Presentation: We report a case of a 48-year-old woman who presented with polyuria, polydipsia, nocturia, and weight loss after a return from a visit to Russia, during which she received a five-day course of antibiotic Demeclocycline, a tetracycline derivative for dental treatment. She recovered from all clinical manifestations by 8 weeks. Conclusion: Manifestation of transient nephrogenic diabetes insipidus is induced by Demeclocycline.

关 键 词：POLYURIA URINE OSMOLARITY Nephrogenic DIABETES Insipidus DEMECLOCYCLINE 

分 类 号：R5[医药卫生—内科学]