DEMECLOCYCLINE

作品数：2被引量：2H指数：1
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相关机构：中南大学更多>>
相关期刊：《Synthetic and Systems Biotechnology》《Open Journal of Endocrine and Metabolic Diseases》更多>>
相关基金：上海市浦江人才计划项目中国博士后科学基金国家自然科学基金更多>>
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Metabolic engineering of a methyltransferase for production of drug precursors demecycline and demeclocycline in Streptomyces aureofaciens被引量：2
《Synthetic and Systems Biotechnology》2020年第3期121-130,共10页Weinan Yang Lingxin Kong Qing Wang Zixin Deng Delin You 
This work was supported by grants from National Key R&D Program of China(2018YFA0900400)from the Ministry of Science and Technology;the National Natural Science Foundation of China(31630002,31770038,31700029,and 21661140002);Shanghai Pujiang Program from the Shanghai Municipal Council of Science and Technology(12PJD021);and China Postdoctoral Science Foundation(2017M620151).
Demecycline(DMTC)and demeclocycline(DMCTC)are C6-demethylated derivatives of tetracycline(TC)and chlortetracycline(CTC),respectively.They are precursors of minocycline and tigecycline,which showed remarkable bioactivi...
关键词：Demecycline DEMECLOCYCLINE Streptomyces aureofaciens F3 Metabolic engineering 
From Russia with Polyuria
《Open Journal of Endocrine and Metabolic Diseases》2015年第5期51-53,共3页DaLim Ki Udaya M. Kabadi 
Introduction: Polyuria is a sign for many disease processes, including diabetes mellitus and diabetes insipidus. Urine osmolarity helps distinguish osmotic diuresis caused by diabetes mellitus from water dieresis indu...
关键词：POLYURIA URINE OSMOLARITY Nephrogenic DIABETES Insipidus DEMECLOCYCLINE 
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