Screening for Precancerous Cervical Lesions in Women of Reproductive Age in the Kara Region of Togo in 2022  

作　　者：Gatibe Yendu-Suglpak Gnatou Zézé Onivogui Latame Komla Adoli Fifonsi Adjidossi Gbeasor-Komlanvi Arnold Junior Sadio Yao Rodion Konu Martin Kouame Tchankoni Wendpouiré Ida Carine Zida-Compaore Amegnona Agbonon Didier Koumavi Ekouevi Gatibe Yendu-Suglpak Gnatou;Zézé Onivogui;Latame Komla Adoli;Fifonsi Adjidossi Gbeasor-Komlanvi;Arnold Junior Sadio;Yao Rodion Konu;Martin Kouame Tchankoni;Wendpouiré Ida Carine Zida-Compaore;Amegnona Agbonon;Didier Koumavi Ekouevi(Department of Public Health, University of Lomé, Faculty of Health Sciences, Lomé, Togo;African Centre for Research in Epidemiology and Public Health (CARESP), Lomé, Togo;Institute of Public Health and Development, University of Bordeaux, Bordeaux, France;French School of Public Health (EHESP), University of Rennes, Rennes, France;Laboratory of Pharmacology and Physiology, University of Lomé, Lomé, Togo;Center for Training and Research in Public Health, University of Lomé, Lomé, Togo)

机构地区：[1]Department of Public Health, University of Lomé, Faculty of Health Sciences, Lomé, Togo [2]African Centre for Research in Epidemiology and Public Health (CARESP), Lomé, Togo [3]Institute of Public Health and Development, University of Bordeaux, Bordeaux, France [4]French School of Public Health (EHESP), University of Rennes, Rennes, France [5]Laboratory of Pharmacology and Physiology, University of Lomé, Lomé, Togo [6]Center for Training and Research in Public Health, University of Lomé, Lomé, Togo

出　　处：《Open Journal of Epidemiology》2023年第4期293-305,共13页流行病学期刊（英文）

摘　　要：Introduction: Worldwide, cervical cancer is the 4^th most common cancer in women and is a public health problem. The objective of this study was to estimate the prevalence of precancerous cervical lesions and to describe its associated factors among women of reproductive age in the Kara region of Togo. Methods: A cross-sectional study was conducted from March 6 to 14, 2022 in 11 health centers in Kara. Data were collected using a standardized questionnaire and screening for precancerous cervical lesions was performed by visual inspection of the cervix, after application of 5% acetic acid and Lugol’s. Logistic regression analysis was performed to describe factors associated with precancerous lesions. Results: A total of 728 women with a median age of 36, interquartile range [31 - 41] were enrolled. The prevalence of precancerous cervical lesions was 3.9%, 95% confidence interval (95% CI: [2.6 - 5.4]. Factors associated with the presence of precancerous lesions were age at first sexual intercourse ≥ 18 years (adjusted odds ratio (aOR = 3.67;95% CI [1.17 - 18.4]) and being a sex worker (aOR = 8.14;95% CI [1.96 - 27.1]). HIV infection was not associated with the presence of precancerous lesions. Conclusion: The results of this study underscore the importance of intensifying cervical cancer screening efforts in resource-limited countries for better management. These efforts should prioritize vulnerable populations such as female sex workers.Introduction: Worldwide, cervical cancer is the 4^th most common cancer in women and is a public health problem. The objective of this study was to estimate the prevalence of precancerous cervical lesions and to describe its associated factors among women of reproductive age in the Kara region of Togo. Methods: A cross-sectional study was conducted from March 6 to 14, 2022 in 11 health centers in Kara. Data were collected using a standardized questionnaire and screening for precancerous cervical lesions was performed by visual inspection of the cervix, after application of 5% acetic acid and Lugol’s. Logistic regression analysis was performed to describe factors associated with precancerous lesions. Results: A total of 728 women with a median age of 36, interquartile range [31 - 41] were enrolled. The prevalence of precancerous cervical lesions was 3.9%, 95% confidence interval (95% CI: [2.6 - 5.4]. Factors associated with the presence of precancerous lesions were age at first sexual intercourse ≥ 18 years (adjusted odds ratio (aOR = 3.67;95% CI [1.17 - 18.4]) and being a sex worker (aOR = 8.14;95% CI [1.96 - 27.1]). HIV infection was not associated with the presence of precancerous lesions. Conclusion: The results of this study underscore the importance of intensifying cervical cancer screening efforts in resource-limited countries for better management. These efforts should prioritize vulnerable populations such as female sex workers.

关 键 词：Precancerous Lesions CERVIX Visual Inspection TOGO 

分 类 号：R73[医药卫生—肿瘤]