Contribution to the Study of the Incidence of Post-Streptococcal Complications in Republic Central African Republic from 2015 to 2018  

作　　者：Zéphirin Dalengat Vogbia Ernest Lango Yaya Jean De Dieu Longo Augustin Balekouzou Gaspard Tekpa Christian Maucler Pamaticka Stéphanie Judith N’Yetobouko Maurel Anicet Adonis Ouoko Fatigbia Christian Diamant Mossoro Kpindet Gérard Gresenguet Zéphirin Dalengat Vogbia;Ernest Lango Yaya;Jean De Dieu Longo;Augustin Balekouzou;Gaspard Tekpa;Christian Maucler Pamaticka;Stéphanie Judith N’Yetobouko;Maurel Anicet Adonis Ouoko Fatigbia;Christian Diamant Mossoro Kpindet;Gérard Gresenguet(Epidemiology and Research Service, National Reference Center for Sexually Transmitted Infections and Anti-Retroviral Therapy, Ministry of Health, Bangui, Central African Republic;Direction of National Laboratory of Clinical Biology and Public Health, Ministry of Health, Bangui, Central African Republic;Training Project Manager and Heald of Public Departement, Ministry of Health, Bangui, Central African Republic;Faculty of Health Sciences, Doctoral School of Human and Veterinary Health Sciences, University of Bangui, Bangui, Central African Republic;National Committee for the Fight against AIDS, Primature, Bangui, Central African Republic;Infectious Disease Department, The Sino Central African Friendship University Hospital Center, Bangui, Central African Republic;Epidemiology Department, Bangui National University Hospital Center, Bangui, Central African Republic)

机构地区：[1]Epidemiology and Research Service, National Reference Center for Sexually Transmitted Infections and Anti-Retroviral Therapy, Ministry of Health, Bangui, Central African Republic [2]Direction of National Laboratory of Clinical Biology and Public Health, Ministry of Health, Bangui, Central African Republic [3]Training Project Manager and Heald of Public Departement, Ministry of Health, Bangui, Central African Republic [4]Faculty of Health Sciences, Doctoral School of Human and Veterinary Health Sciences, University of Bangui, Bangui, Central African Republic [5]National Committee for the Fight against AIDS, Primature, Bangui, Central African Republic [6]Infectious Disease Department, The Sino Central African Friendship University Hospital Center, Bangui, Central African Republic [7]Epidemiology Department, Bangui National University Hospital Center, Bangui, Central African Republic

出　　处：《Open Journal of Epidemiology》2024年第1期110-121,共12页流行病学期刊（英文）

摘　　要：Introduction: Acute rheumatic fever (AAR) is a non-suppurative complication of late infection by group A. Infections due to streptococci remain a public health problem in the Central African Republic. The present study aims to determine the incidence rate of AAR cases and its complications. Methodology: This was a retrospective and analytical study over a period of 4 years (from January 2015 to December 2018) at the National Laboratory of Clinical Biology and Public Health (LNBCSP) in Bangui. It focused on samples concerning the diagnosis of AAR and patient files seen in consultation in the capital’s reference health establishments. Laboratory registers and patient consultation files were used to collect data. They were entered into Excel 2010 to be analyzed with Epi Info 7. A univariate analysis by logistic regression, Ficher’s exact test, and chi² at the 5% threshold (p Results: We analyzed 94 cases meeting Jones’s criteria. The ages of the patients ranged from 18 to 85 years (mean age 52 years and mode 45 years). The incidence rate of AAR for the female sex was higher than that of the male sex during the study period (p > 0.05). It went from 166.6 in 2015 to 200 in 2016 and 2018 cases of AAR per 1000 people per year. The average incidence rate was 296.18 cases of AAR per 1000 people per year. The average incidence rate was 223.5 cases of AAR per 1000 people per year for joint damage. Joint damage represented 80.85% (RR = 0.62;Chi² = 4.88;95% CI [0.39-0.97];p Conclusion: The study allowed data on the impact rate and complications of the AAR in Bangui. Special attention to data management will help produce a complete result on the problem. Joint complications predominated. Sustaining an effective surveillance system and preventing infection would help reduce the risk of AAR occurrence.Introduction: Acute rheumatic fever (AAR) is a non-suppurative complication of late infection by group A. Infections due to streptococci remain a public health problem in the Central African Republic. The present study aims to determine the incidence rate of AAR cases and its complications. Methodology: This was a retrospective and analytical study over a period of 4 years (from January 2015 to December 2018) at the National Laboratory of Clinical Biology and Public Health (LNBCSP) in Bangui. It focused on samples concerning the diagnosis of AAR and patient files seen in consultation in the capital’s reference health establishments. Laboratory registers and patient consultation files were used to collect data. They were entered into Excel 2010 to be analyzed with Epi Info 7. A univariate analysis by logistic regression, Ficher’s exact test, and chi² at the 5% threshold (p Results: We analyzed 94 cases meeting Jones’s criteria. The ages of the patients ranged from 18 to 85 years (mean age 52 years and mode 45 years). The incidence rate of AAR for the female sex was higher than that of the male sex during the study period (p > 0.05). It went from 166.6 in 2015 to 200 in 2016 and 2018 cases of AAR per 1000 people per year. The average incidence rate was 296.18 cases of AAR per 1000 people per year. The average incidence rate was 223.5 cases of AAR per 1000 people per year for joint damage. Joint damage represented 80.85% (RR = 0.62;Chi² = 4.88;95% CI [0.39-0.97];p Conclusion: The study allowed data on the impact rate and complications of the AAR in Bangui. Special attention to data management will help produce a complete result on the problem. Joint complications predominated. Sustaining an effective surveillance system and preventing infection would help reduce the risk of AAR occurrence.

关 键 词：INCIDENCE Acute Joint Rheumatism Central African Republic 

分 类 号：R73[医药卫生—肿瘤]