Post-Endoscopy Self-Limited Unspecified Fever: Rare or Common Adverse Event after Endoscopy?—An Observational, Cross-Sectional Study  

作　　者：Boris Tufegdzic Guus Jansen Lina Hussein Valsala Visno Terrence J. Lee-St. John Massimo Lamperti Boris Tufegdzic;Guus Jansen;Lina Hussein;Valsala Visno;Terrence J. Lee-St. John;Massimo Lamperti(Anaesthesiology Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE;Digestive Disease Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE;Research Department, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE)

机构地区：[1]Anaesthesiology Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE [2]Digestive Disease Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE [3]Research Department, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE

出　　处：《Open Journal of Gastroenterology》2022年第8期192-203,共12页肠胃病学期刊（英文）

摘　　要：Background: Although post-endoscopy fever (PEF) without colon perforation or haemorrhage is believed to be rare, incidence, risk factors and causes in the adult population have not been fully investigated. The purpose of the present study was to investigate the incidence of PEF and identify the risk factors associated with the development of PEF and its outcomes. Material and Methods: Over a three-month period, 1054 non-hospitalised patients who had an endoscopic procedure at Cleveland Clinic Abu Dhabi received a post-procedure phone call within the first 24 hours. After identifying patients with fever and obtaining verbal consent, patients were enrolled in the study using a standardised telephone interview. Results: Thirty-four patients with PEF were identified. The highest temperature measured was 39.8 degrees Celsius. Oesophagogastroduodenoscopy, as a single procedure, was the most commonly performed (41.2%). Logistic regression revealed that no significant group differences across procedure types existed in terms of adjusted odds of fever. However, results also indicated that age has a significant negative relationship with fever—higher age is associated with lower odds of fever (b = -0.033, p = 0.024). Conclusion: PEF is an unpleasant side effect and it is associated with patient discomfort, dissatisfaction and fear during post-endoscopy recovery. Although our findings do not fully explain the possible mechanisms underlying post-endoscopy fever, this study data should increase awareness about PEF as a common side effect related to endoscopy.Background: Although post-endoscopy fever (PEF) without colon perforation or haemorrhage is believed to be rare, incidence, risk factors and causes in the adult population have not been fully investigated. The purpose of the present study was to investigate the incidence of PEF and identify the risk factors associated with the development of PEF and its outcomes. Material and Methods: Over a three-month period, 1054 non-hospitalised patients who had an endoscopic procedure at Cleveland Clinic Abu Dhabi received a post-procedure phone call within the first 24 hours. After identifying patients with fever and obtaining verbal consent, patients were enrolled in the study using a standardised telephone interview. Results: Thirty-four patients with PEF were identified. The highest temperature measured was 39.8 degrees Celsius. Oesophagogastroduodenoscopy, as a single procedure, was the most commonly performed (41.2%). Logistic regression revealed that no significant group differences across procedure types existed in terms of adjusted odds of fever. However, results also indicated that age has a significant negative relationship with fever—higher age is associated with lower odds of fever (b = -0.033, p = 0.024). Conclusion: PEF is an unpleasant side effect and it is associated with patient discomfort, dissatisfaction and fear during post-endoscopy recovery. Although our findings do not fully explain the possible mechanisms underlying post-endoscopy fever, this study data should increase awareness about PEF as a common side effect related to endoscopy.

关 键 词：Post Endoscopy Fever Drug-Induced Fever Bacteria Translocation 

分 类 号：R73[医药卫生—肿瘤]