Seroprevalence, Importance of Rapid Testing and Factors Associated with HBsAg Carriage in Pregnancy in Three Referral Maternity Hospitals in Mono (Benin), in 2020  

作　　者：Aboudou Raïmi Kpossou Djima Patrice Dangbemey Véronique Mèdessè Tognifodé Barnard Acakpo Jean Sehonou Josiane Angeline Tonato Bagnan Aboudou Raïmi Kpossou;Djima Patrice Dangbemey;Véronique Mèdessè Tognifodé;Barnard Acakpo;Jean Sehonou;Josiane Angeline Tonato Bagnan(Faculty of Health Sciences, University of Abomey-Calavi, Cotonou, Republic of Benin;Hepato-Gastroenterology Department, National and University Hospital Hubert Koutoukou Maga (CNHU-HKM), Cotonou, Repub-lic of Benin;Obstetrics Gynecology Department, Lagune Mother-Child University Hospital Center (CHU MEL), Cotonou, Republic of Benin)

机构地区：[1]Faculty of Health Sciences, University of Abomey-Calavi, Cotonou, Republic of Benin [2]Hepato-Gastroenterology Department, National and University Hospital Hubert Koutoukou Maga (CNHU-HKM), Cotonou, Repub-lic of Benin [3]Obstetrics Gynecology Department, Lagune Mother-Child University Hospital Center (CHU MEL), Cotonou, Republic of Benin

出　　处：《Open Journal of Gastroenterology》2023年第9期279-298,共20页肠胃病学期刊（英文）

摘　　要：Introduction Difficulties in accessing the screening test for viral hepatitis B in maternity wards could be a factor in underestimating the prevalence of anti-HBV antibodies. The rapid diagnostic orientation test (RDOT) could improve seroprevalence and obstetrical prognosis. The aim of this study was to use the rapid diagnostic orientation test (RDOT) to determine the seroprevalence of HBs antigen carriage in pregnant women while highlighting the associated factors. Methods This was a cross-sectional and descriptive study that took place from October to December 2020 (three months) in three (03) reference maternities in western Benin (Mono). Consenting pregnant women received in prenatal consultation had been screened by RDOT. Positive cases were confirmed by ELISA test. The follow-up of these cases made it possible to establish the obstetrical prognosis. Results Of 201 women studied, 11 (5.5%) were positive for RDOT HBV and confirmed by the ELISA test. The factors associated with HBsAg carriage during pregnancy were multiple sexual partnerships (p = 0.01), female circumcision (p = 0.0001), and ignorance of prior HBV serological status (p = 0.0001). No influence of hepatitis B on pregnancy was noted. Conclusion The seroprevalence of hepatitis B in pregnancy was intermediate in the reference maternities of western Benin. The associated factors were multiple sexual partnerships, female circumcision and unawareness of prior HBV status. Free RDOT in maternity wards would improve early detection and management of viral hepatitis B in pregnancy.Introduction Difficulties in accessing the screening test for viral hepatitis B in maternity wards could be a factor in underestimating the prevalence of anti-HBV antibodies. The rapid diagnostic orientation test (RDOT) could improve seroprevalence and obstetrical prognosis. The aim of this study was to use the rapid diagnostic orientation test (RDOT) to determine the seroprevalence of HBs antigen carriage in pregnant women while highlighting the associated factors. Methods This was a cross-sectional and descriptive study that took place from October to December 2020 (three months) in three (03) reference maternities in western Benin (Mono). Consenting pregnant women received in prenatal consultation had been screened by RDOT. Positive cases were confirmed by ELISA test. The follow-up of these cases made it possible to establish the obstetrical prognosis. Results Of 201 women studied, 11 (5.5%) were positive for RDOT HBV and confirmed by the ELISA test. The factors associated with HBsAg carriage during pregnancy were multiple sexual partnerships (p = 0.01), female circumcision (p = 0.0001), and ignorance of prior HBV serological status (p = 0.0001). No influence of hepatitis B on pregnancy was noted. Conclusion The seroprevalence of hepatitis B in pregnancy was intermediate in the reference maternities of western Benin. The associated factors were multiple sexual partnerships, female circumcision and unawareness of prior HBV status. Free RDOT in maternity wards would improve early detection and management of viral hepatitis B in pregnancy.

关 键 词：Hepatitis B SEROPREVALENCE Associated Factors Rapid Test BENIN 

分 类 号：R51[医药卫生—内科学]