Therapeutic Profile and Prognostic Factors of Patients Suffering from Upper Digestive Bleeding at Sikasso Regional Hospital  

作　　者：Oumar Traoré Abdoul Salam Diarra Dramane Touré Tawfiq Abu Amadou Boubeye Maïga Kadiatou Cissé Saïdon Touré Mohomedine Touré Aboudou Dolo Youana Koné Madou Traoré Mamadou Togo Kalba Péliaba Mamadou Samaké Hamadoun Sangho Oumar Traoré;Abdoul Salam Diarra;Dramane Touré;Tawfiq Abu;Amadou Boubeye Maïga;Kadiatou Cissé;Saïdon Touré;Mohomedine Touré;Aboudou Dolo;Youana Koné;Madou Traoré;Mamadou Togo;Kalba Péliaba;Mamadou Samaké;Hamadoun Sangho(Service of Internal Medicine, Regional Hospital, Sikasso, Mali;National Center for Scientific and Technological Research, Bamako, Mali;Department of Pediatric, Health Referral Center of Kalaban Coro, Koulikoro, Mali;Private Practice for Family and Emergency Medicine, Casablanca, Morocco;Service of Nephrology, Regional Hospital, Sikasso, Mali;Department of Infectious Disease, Regional Hospital, Sikasso, Mali;Service de Mdecine Interne, CHU Gabriel Tour, Bamako, Mali;Service dHpato-Gastro-Entrologie, CHU Gabriel Tour, Bamako, Mali;Department of Public Health, Faculty of Medicine and Odontostomatology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali)

机构地区：[1]Service of Internal Medicine, Regional Hospital, Sikasso, Mali [2]National Center for Scientific and Technological Research, Bamako, Mali [3]Department of Pediatric, Health Referral Center of Kalaban Coro, Koulikoro, Mali [4]Private Practice for Family and Emergency Medicine, Casablanca, Morocco [5]Service of Nephrology, Regional Hospital, Sikasso, Mali [6]Department of Infectious Disease, Regional Hospital, Sikasso, Mali [7]Service de Mdecine Interne, CHU Gabriel Tour, Bamako, Mali [8]Service dHpato-Gastro-Entrologie, CHU Gabriel Tour, Bamako, Mali [9]Department of Public Health, Faculty of Medicine and Odontostomatology, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali

出　　处：《Open Journal of Gastroenterology》2024年第9期300-312,共13页肠胃病学期刊（英文）

摘　　要：Introduction: Upper digestive hemorrhage is one of the main digestive emergencies and remains a major cause of morbidity and mortality in Mali. The aim of this study was to describe the therapeutic profile and outcome of patients suffering from upper digestive haemorrhage. Methodology: This was a prospective study carried out in the internal medicine department of the Sikasso Regional Hospital from August 2022 to July 2023. All adult patients presenting with upper digestive haemorrhage and having given their consent, were included. Data were analyzed using SPSS version 21 software. Results: Sixty-three patients were enrolled. The mean age was 49.7 ± 18.99 years, with a male-female sex ratio of 2.2. Ruptured esophageal varices (37.5%) and peptic ulcer (25%) were the main etiologies. Pharmacological treatment was dominated by proton pump inhibitors (85.7%). Hemostasis endoscopy accounted for 3.17%. The evolution was marked by hemorrhagic arrest (69.84%), recurrence of hemorrhage (11.11%) and death (19.04%), the main cause of which was hemorrhagic shock (58.3%). We found no statistically significant relationship between prognosis and etiologies (P = 0.11), and length of hospital stay (P = 0.18). Conclusion: Hemostasis endoscopy remains a challenge for Sikasso Hospital. A holistic strategy of communication and community awareness-raising, combined with adequate technical facilities, will help to improve patient care and outcomes.Introduction: Upper digestive hemorrhage is one of the main digestive emergencies and remains a major cause of morbidity and mortality in Mali. The aim of this study was to describe the therapeutic profile and outcome of patients suffering from upper digestive haemorrhage. Methodology: This was a prospective study carried out in the internal medicine department of the Sikasso Regional Hospital from August 2022 to July 2023. All adult patients presenting with upper digestive haemorrhage and having given their consent, were included. Data were analyzed using SPSS version 21 software. Results: Sixty-three patients were enrolled. The mean age was 49.7 ± 18.99 years, with a male-female sex ratio of 2.2. Ruptured esophageal varices (37.5%) and peptic ulcer (25%) were the main etiologies. Pharmacological treatment was dominated by proton pump inhibitors (85.7%). Hemostasis endoscopy accounted for 3.17%. The evolution was marked by hemorrhagic arrest (69.84%), recurrence of hemorrhage (11.11%) and death (19.04%), the main cause of which was hemorrhagic shock (58.3%). We found no statistically significant relationship between prognosis and etiologies (P = 0.11), and length of hospital stay (P = 0.18). Conclusion: Hemostasis endoscopy remains a challenge for Sikasso Hospital. A holistic strategy of communication and community awareness-raising, combined with adequate technical facilities, will help to improve patient care and outcomes.

关 键 词：Digestive Hemorrhage Digestive Endoscopy Treatment OUTCOME 

分 类 号：R73[医药卫生—肿瘤]