Patient Blood Management in Craniosynostosis Surgery  

作　　者：Claudine Kumba Claudine Kumba(Department of Pediatric and Obstetric Anesthesia and Critical Care, Hôpital Universitaire Necker Enfants Malades, Assistance Publique Hôpitaux de Paris, APHP, Université de Paris, Paris, France)

机构地区：[1]Department of Pediatric and Obstetric Anesthesia and Critical Care, Hô pital Universitaire Necker Enfants Malades, Assistance Publique Hô pitaux de Paris, APHP, Université de Paris, Paris, France

出　　处：《Open Journal of Modern Neurosurgery》2021年第4期211-222,共12页现代神经外科学进展（英文）

摘　　要：<b><span style="font-family:Verdana;">Background:</span></b><span style="font-family:Verdana;"> Craniosynostosis surgery is one of the most hemorrhagic interventions, where transfusion rates vary from 20</span><span style="font-family:Verdana;">%</span><span style="font-family:""><span style="font-family:Verdana;"> to 100% depending on the study. </span><b><span style="font-family:Verdana;">Objective: </span></b><span style="font-family:Verdana;">To describe intraoperative and postoperative outcomes in a secondary analysis of children who underwent craniosynostosis surgery included in the initial retrospective study with the aim of proposing intraoperative implementation optimization protocols for postoperative outcome improvement. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> Secondary analysis. The study was approved by the </span><span><span style="font-family:Verdana;">Ethics Committee. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">There were 69 children with a median age of 10 </span></span></span><span style="font-family:Verdana;">[</span><span style="font-family:Verdana;">0</span><span style="font-family:Verdana;"> - </span><span style="font-family:Verdana;">207</span><span style="font-family:Verdana;">]</span><span style="font-family:""><span style="font-family:Verdana;"> months. Eight (11.6%) patients had intraoperative and/or postoperative complications. One patient (1.5%) had intraoperative hemorrhagic shock, and two patients (2.9%) had intraoperative broncholaryngospasm. One patient (1.5%) had postoperative anaphylaxis. One patient (1.5%) had postoperative hemorrhagic shock. One patient (1.5%) had postoperative respiratory failure. Two patients (2.9%) had postoperative neurologic failure. One patient (1.5%) had neuro-meningeal sepsis. One patient (1.5%) had a re-operation. There was no in-hospital mortality. Fourty-eight patients (69.6%) had intraoperative transfusions. </span><b><span style="fo<b><span style="font-family:Verdana;">Background:</span></b><span style="font-family:Verdana;"> Craniosynostosis surgery is one of the most hemorrhagic interventions, where transfusion rates vary from 20</span><span style="font-family:Verdana;">%</span><span style="font-family:""><span style="font-family:Verdana;"> to 100% depending on the study. </span><b><span style="font-family:Verdana;">Objective: </span></b><span style="font-family:Verdana;">To describe intraoperative and postoperative outcomes in a secondary analysis of children who underwent craniosynostosis surgery included in the initial retrospective study with the aim of proposing intraoperative implementation optimization protocols for postoperative outcome improvement. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> Secondary analysis. The study was approved by the </span><span><span style="font-family:Verdana;">Ethics Committee. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">There were 69 children with a median age of 10 </span></span></span><span style="font-family:Verdana;">[</span><span style="font-family:Verdana;">0</span><span style="font-family:Verdana;"> - </span><span style="font-family:Verdana;">207</span><span style="font-family:Verdana;">]</span><span style="font-family:""><span style="font-family:Verdana;"> months. Eight (11.6%) patients had intraoperative and/or postoperative complications. One patient (1.5%) had intraoperative hemorrhagic shock, and two patients (2.9%) had intraoperative broncholaryngospasm. One patient (1.5%) had postoperative anaphylaxis. One patient (1.5%) had postoperative hemorrhagic shock. One patient (1.5%) had postoperative respiratory failure. Two patients (2.9%) had postoperative neurologic failure. One patient (1.5%) had neuro-meningeal sepsis. One patient (1.5%) had a re-operation. There was no in-hospital mortality. Fourty-eight patients (69.6%) had intraoperative transfusions. </span><b><span style="fo

关 键 词：CRANIOSYNOSTOSIS Children TRANSFUSION OUTCOME Point of Care Viscoelastic Assays Rotational Thromboelastometry 

分 类 号：R73[医药卫生—肿瘤]