Evaluation of the Neurodevelopmental Outcome of Toddlers with Spinal Dysraphism after Surgical Repair Using ASQ-3^™ Scores  

作　　者：Mujahid Imam Fawaz Eljili Marhoom Sawsan Aldeaf Ali Awad Ahmed Zidan Mohamed Mustafa Ahmed Sanna Taha Mujahid Imam;Fawaz Eljili Marhoom;Sawsan Aldeaf;Ali Awad;Ahmed Zidan;Mohamed Mustafa Ahmed;Sanna Taha(Neurosurgery Department, National Center for Neurological Sciences (NCNS), Khartoum, Sudan;Neurosurgery Department, Royal Care International Hospital, Khartoum, Sudan;Al Ribat Neurospine Center, Khartoum, Sudan;Neurosurgery Department, Haj Almardi (Al Tamyouz) Hospital, Khartoum, Sudan;Neurosurgery Department, Al Jazeera Trauma Center, Khartoum, Sudan)

机构地区：[1]Neurosurgery Department, National Center for Neurological Sciences (NCNS), Khartoum, Sudan [2]Neurosurgery Department, Royal Care International Hospital, Khartoum, Sudan [3]Al Ribat Neurospine Center, Khartoum, Sudan [4]Neurosurgery Department, Haj Almardi (Al Tamyouz) Hospital, Khartoum, Sudan [5]Neurosurgery Department, Al Jazeera Trauma Center, Khartoum, Sudan

出　　处：《Open Journal of Modern Neurosurgery》2024年第1期14-29,共16页现代神经外科学进展（英文）

摘　　要：Background: Spinal dysraphism represents a wide spectrum of congenital abnormalities of the spine. Myelomeningocele is considered the most common malformation and the most common we saw in our community, with its morbidity problems seen commonly in the postoperative period. ASQ-3^TM Scores are the ages and stages questionnaire, third edition, and represent a tool to assess the development progress, especially in toddlers. Objectives: Evaluation of neurodevelopmental outcome among Sudanese toddlers with spinal dysraphism after surgical closure with or without a VP shunt using ASQ-3^TM Scores. Methodology: This is a retrospective hospital-based study of 84 patients who underwent myelomeningocele repair at the National Center for Neurological Sciences (NCNS) during the period from 2017 up to 2019. Data were collected through a constructed questionnaire, including ASQ-3^TM Scores. Data were processed and analyzed using the Statistical Package for Social Science (SPSS) computer program. Version 25. Results: 84 patients were included in this study;all patients were diagnosed with spinal dysraphism. Out of them, 51 (60.7%) were 2 years old, 33 (39.3%) were 3 years old, 45 (53.6%) were male, 45 (53.6%) of patients mothers attended ANC irregularly, and 54 (64.3%) their mothers didn’t receive folate supplements. 44 (52.3%) of patients underwent MMC repair only, while 40 (47.7%) underwent MMC repair and VP shunt. The commonest postoperative complication was infection, reported in 12 (14.3%) of patients, followed by VP shunt revision in 9 (10.7%) of patients. Neurological assessment showed that the majority of patients need further assessment with a professional, 57 (67.9%) of children don’t walk, run, or climb like other toddlers as their parent’s state;also, half of patients (42, 50%) had medical problems, and 27 (32.1%) of their parent’s state that they do not talk like other toddlers their age. There was a statistically significant association between post-operative complications andBackground: Spinal dysraphism represents a wide spectrum of congenital abnormalities of the spine. Myelomeningocele is considered the most common malformation and the most common we saw in our community, with its morbidity problems seen commonly in the postoperative period. ASQ-3^TM Scores are the ages and stages questionnaire, third edition, and represent a tool to assess the development progress, especially in toddlers. Objectives: Evaluation of neurodevelopmental outcome among Sudanese toddlers with spinal dysraphism after surgical closure with or without a VP shunt using ASQ-3^TM Scores. Methodology: This is a retrospective hospital-based study of 84 patients who underwent myelomeningocele repair at the National Center for Neurological Sciences (NCNS) during the period from 2017 up to 2019. Data were collected through a constructed questionnaire, including ASQ-3^TM Scores. Data were processed and analyzed using the Statistical Package for Social Science (SPSS) computer program. Version 25. Results: 84 patients were included in this study;all patients were diagnosed with spinal dysraphism. Out of them, 51 (60.7%) were 2 years old, 33 (39.3%) were 3 years old, 45 (53.6%) were male, 45 (53.6%) of patients mothers attended ANC irregularly, and 54 (64.3%) their mothers didn’t receive folate supplements. 44 (52.3%) of patients underwent MMC repair only, while 40 (47.7%) underwent MMC repair and VP shunt. The commonest postoperative complication was infection, reported in 12 (14.3%) of patients, followed by VP shunt revision in 9 (10.7%) of patients. Neurological assessment showed that the majority of patients need further assessment with a professional, 57 (67.9%) of children don’t walk, run, or climb like other toddlers as their parent’s state;also, half of patients (42, 50%) had medical problems, and 27 (32.1%) of their parent’s state that they do not talk like other toddlers their age. There was a statistically significant association between post-operative complications and

关 键 词：Toddlers’ Neurodevelopmental Outcome Myelomeningocele Evaluation ASQ-3^™ Scores Spinal Dysraphasim Neurodevelopmental Outcome 

分 类 号：R73[医药卫生—肿瘤]