Calcific Uremic Arteriolopathy or Calciphylaxis in a Hemodialysis Patient: Case Study and Review of the Literature  

作　　者：Modou Ndongo Nestor Nankeu Josephine Nkok Helene Messet Fabrice Tiako Mamadou Mouctar Diallo Misylias Bouaoud Attia Houyem Fatiha Lahouel Djillali Ziane Berroudja Tayeb Bensalem Sid Ali Toufik Benyaghla Catherine Albert Sidy Mohamed Seck El Hadji Fary Ka Modou Ndongo;Nestor Nankeu;Josephine Nkok;Helene Messet;Fabrice Tiako;Mamadou Mouctar Diallo;Misylias Bouaoud;Attia Houyem;Fatiha Lahouel;Djillali Ziane Berroudja;Tayeb Bensalem;Sid Ali Toufik Benyaghla;Catherine Albert;Sidy Mohamed Seck;El Hadji Fary Ka(Department of Nephrology, Dialysis and Kidney Transplantation of Aristide Le Dantec Hospital, Dakar, Senegal;Department of Nephrology, Dialysis of Louis Pasteur Hospital, Chartres, France;Department of Nephrology, Dialysis of Ouakam Military Hospital, Dakar, Senegal)

机构地区：[1]Department of Nephrology, Dialysis and Kidney Transplantation of Aristide Le Dantec Hospital, Dakar, Senegal [2]Department of Nephrology, Dialysis of Louis Pasteur Hospital, Chartres, France [3]Department of Nephrology, Dialysis of Ouakam Military Hospital, Dakar, Senegal

出　　处：《Open Journal of Nephrology》2022年第3期303-310,共8页肾脏病（英文）

摘　　要：Calcific uremic arteriolopathy (CUA) is a rare pathology affecting 5% of dialysis patients but with a poor prognosis. It is characterized by calcification and thrombotic lesions of the microcirculation leading to hyperalgesic ischemic skin lesions. Several risk factors have been identified, mainly warfarin treatment, mineral and bone disorders (MBD), inflammation and malnutrition. In the evocative forms, the diagnosis is made based upon the physical examination finding of classic painful ulcerated lesions that are covered by a black eschar. Skin biopsy, due to the risk of aggravation and delayed healing, is only performed in case of doubt diagnosis. The therapeutic attitude due to the lack of solid randomized studies is based on expert consensus and requires a multidisciplinary approach. We report here the case of a patient with CUA revealed in the form of multiple ulcerative-necrotic skin lesions associated with pressure sores and arterial wounds.Calcific uremic arteriolopathy (CUA) is a rare pathology affecting 5% of dialysis patients but with a poor prognosis. It is characterized by calcification and thrombotic lesions of the microcirculation leading to hyperalgesic ischemic skin lesions. Several risk factors have been identified, mainly warfarin treatment, mineral and bone disorders (MBD), inflammation and malnutrition. In the evocative forms, the diagnosis is made based upon the physical examination finding of classic painful ulcerated lesions that are covered by a black eschar. Skin biopsy, due to the risk of aggravation and delayed healing, is only performed in case of doubt diagnosis. The therapeutic attitude due to the lack of solid randomized studies is based on expert consensus and requires a multidisciplinary approach. We report here the case of a patient with CUA revealed in the form of multiple ulcerative-necrotic skin lesions associated with pressure sores and arterial wounds.

关 键 词：Calcific Uremic Arteriolopathy CALCIPHYLAXIS HEMODIALYSIS 

分 类 号：R73[医药卫生—肿瘤]