The relationship between second trimester alpha fetoprotein levels and adverse pregnancy outcome  

作　　者：Rebecca Allen Shemoon Marleen Luxmi Velauthar Kevin Harrington Joseph Aquilina 

机构地区：[1]Department of Fetal Medicine, Royal London Hospital, London, UK [2]Portland Hospital, Great Portland Street, London, UK

出　　处：《Open Journal of Obstetrics and Gynecology》2013年第2期262-266,共5页妇产科期刊（英文）

摘　　要：Design: Retrospective analysis. Setting: East London Hospital. Subjects: 724 women who had maternal serum alphafetoprotein levels measured between 15 to 19 weeks gestation. Main outcome measure: The main outcome measures were defined as any case of preeclampsia, small-for-gestational age (SGA) birth- weight th centile, placental abruption, stillbirth or early neonatal death. Methods: Women with MSAFP > 2.0 Multiples of Median (MoM) were classified as screen positive. Results: 41 (5.7%) women developed preeclampsia. Women with MSAFP > 2.0 Multiples of the Median (MoM) were significantly more likely to develop preeclampsia (p th centileDesign: Retrospective analysis. Setting: East London Hospital. Subjects: 724 women who had maternal serum alphafetoprotein levels measured between 15 to 19 weeks gestation. Main outcome measure: The main outcome measures were defined as any case of preeclampsia, small-for-gestational age (SGA) birth- weight th centile, placental abruption, stillbirth or early neonatal death. Methods: Women with MSAFP > 2.0 Multiples of Median (MoM) were classified as screen positive. Results: 41 (5.7%) women developed preeclampsia. Women with MSAFP > 2.0 Multiples of the Median (MoM) were significantly more likely to develop preeclampsia (p th centile (p

关 键 词：AFP Alpha Fetoprotein PRE-ECLAMPSIA Small for GESTATIONAL Age STILL BIRTH PLACENTAL ABRUPTION 

分 类 号：R73[医药卫生—肿瘤]