Feasibility of Complete Cytoreduction in Advanced Epithelial Ovarian Cancer  

作　　者：Noha E. Hassan Abdel Fattah Agameya Amal Alsonoussi Mahmoud Meleis Noha E. Hassan;Abdel Fattah Agameya;Amal Alsonoussi;Mahmoud Meleis(Obstetrics and Gynecology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt)

机构地区：[1]Obstetrics and Gynecology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt

出　　处：《Open Journal of Obstetrics and Gynecology》2021年第7期836-844,共9页妇产科期刊（英文）

摘　　要：<strong>Objective:</strong><span style="font-family:Verdana;"> Complete resectability of all visualized tumor implants at debulking surgery for advanced epithelial ovarian cancer is confirmed to be the s</span><span style="font-family:""><span style="font-family:Verdana;">ingle most important prognostic factor. This study aims</span><b> </b><span style="font-family:Verdana;">to develop </span><span style="font-family:Verdana;">preoperative</span><span style="font-family:Verdana;"> predicting score based on clinical, biological, and radiological criteria of epithelial ovarian cancer to assess the feasibility of complete cytoreduction. </span><b><span style="font-family:Verdana;">Study Design: </span></b><span style="font-family:Verdana;">A retrospective record-based study. </span><b><span style="font-family:Verdana;">Patients and Methods: </span></b><span style="font-family:Verdana;">The study was conducted upon 50 consecutive patients managed for epithelial ovarian cancer with FIGO stage III. Patients’ data were collected from records of the Gyne-Oncology Clinic of El Shatby University Maternity Hospital affiliated </span><span style="font-family:Verdana;">to</span><span style="font-family:Verdana;"> Alexandria University. </span><b><span style="font-family:Verdana;">Results:</span></b></span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">Many parameters were significantly associated with completeness of resectability in univariate analysis;including age, BMI, CA125, albumin, pre-albumin, PCI, mesenteric, and right copula of diaphragm affection by CT scan (</span><span style="font-family:Verdana;">p value</span><span style="font-family:Verdana;"> < 0</span></span><span style="font-family:Verdana;">.</span><span style="font-family:Verdana;">05). A 100-point predictability score was developed, 10 for BMI ≥</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">35 kg/m</span><sup><span style="font-family:Verdana<strong>Objective:</strong><span style="font-family:Verdana;"> Complete resectability of all visualized tumor implants at debulking surgery for advanced epithelial ovarian cancer is confirmed to be the s</span><span style="font-family:""><span style="font-family:Verdana;">ingle most important prognostic factor. This study aims</span><b> </b><span style="font-family:Verdana;">to develop </span><span style="font-family:Verdana;">preoperative</span><span style="font-family:Verdana;"> predicting score based on clinical, biological, and radiological criteria of epithelial ovarian cancer to assess the feasibility of complete cytoreduction. </span><b><span style="font-family:Verdana;">Study Design: </span></b><span style="font-family:Verdana;">A retrospective record-based study. </span><b><span style="font-family:Verdana;">Patients and Methods: </span></b><span style="font-family:Verdana;">The study was conducted upon 50 consecutive patients managed for epithelial ovarian cancer with FIGO stage III. Patients’ data were collected from records of the Gyne-Oncology Clinic of El Shatby University Maternity Hospital affiliated </span><span style="font-family:Verdana;">to</span><span style="font-family:Verdana;"> Alexandria University. </span><b><span style="font-family:Verdana;">Results:</span></b></span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">Many parameters were significantly associated with completeness of resectability in univariate analysis;including age, BMI, CA125, albumin, pre-albumin, PCI, mesenteric, and right copula of diaphragm affection by CT scan (</span><span style="font-family:Verdana;">p value</span><span style="font-family:Verdana;"> < 0</span></span><span style="font-family:Verdana;">.</span><span style="font-family:Verdana;">05). A 100-point predictability score was developed, 10 for BMI ≥</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">35 kg/m</span><sup><span style="font-family:Verdana

关 键 词：CYTOREDUCTION Ovarian Carcinoma Predictive Score 

分 类 号：R73[医药卫生—肿瘤]