The Place of Nipple-Sparing Mastectomy in the Treatment of Breast Cancer: Review of the Literature  

作　　者：Abdallah El Farouqi Anas Boumzough Abdallah El Farouqi;Anas Boumzough(Department of Obstetrics and Gynecology, Agadir Faculty of Medicine and Pharmacy, UHC Agadir, Morocco)

机构地区：[1]Department of Obstetrics and Gynecology, Agadir Faculty of Medicine and Pharmacy, UHC Agadir, Morocco

出　　处：《Open Journal of Obstetrics and Gynecology》2021年第12期1752-1769,共18页妇产科期刊（英文）

摘　　要：<strong>Introduction:</strong><span style="font-family:""><span style="font-family:Verdana;"> Mastectomy with conservation of the nipple-areola complex (NAC) in breast cancer care has been controversial with regards to the oncological safety of this procedure and the risk of complications including NAC necrosis. </span><b><span style="font-family:Verdana;">Aim: </span></b><span style="font-family:Verdana;">The objective of this study is to assess, through a literature review, the safety and reliability of a conservative NAC mastectomy in breast cancer treatment, paying attention to the rate of local recurrence and complications. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> A review of the literature was conducted from PubMed data, and articles published between January 2007 and December 2017, using the terms </span></span><span style="font-family:Verdana;">“</span><span style="font-family:""><span style="font-family:Verdana;">nipple-sparing mastectomy”, “breast cancer”, “local recu</span><span style="font-family:Verdana;">rrence”, “necrosis of the nipple”, “global complications”. The articles were</span><span style="font-family:Verdana;"> analyzed with regards to the following parameters of evaluation: local recurrence, recurrence rate at NAC level, global complication rates and nipple necrosis rates. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> In the 36 studies we selected, the average rate of local recurrence was 3.23%. The average rate of recurrence at the NAC was 0.81%. The average rate of complications was 20%. The average rate of necrosis of the NAC was 5.9%. The main factors of these recurrences were the tumor size > 5 cm and tumor stage > stage II. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> Conservative mastectomy of the nipple-areola complex offers an aesthetic advantage and oncological safety in carefully selected p<strong>Introduction:</strong><span style="font-family:""><span style="font-family:Verdana;"> Mastectomy with conservation of the nipple-areola complex (NAC) in breast cancer care has been controversial with regards to the oncological safety of this procedure and the risk of complications including NAC necrosis. </span><b><span style="font-family:Verdana;">Aim: </span></b><span style="font-family:Verdana;">The objective of this study is to assess, through a literature review, the safety and reliability of a conservative NAC mastectomy in breast cancer treatment, paying attention to the rate of local recurrence and complications. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> A review of the literature was conducted from PubMed data, and articles published between January 2007 and December 2017, using the terms </span></span><span style="font-family:Verdana;">“</span><span style="font-family:""><span style="font-family:Verdana;">nipple-sparing mastectomy”, “breast cancer”, “local recu</span><span style="font-family:Verdana;">rrence”, “necrosis of the nipple”, “global complications”. The articles were</span><span style="font-family:Verdana;"> analyzed with regards to the following parameters of evaluation: local recurrence, recurrence rate at NAC level, global complication rates and nipple necrosis rates. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> In the 36 studies we selected, the average rate of local recurrence was 3.23%. The average rate of recurrence at the NAC was 0.81%. The average rate of complications was 20%. The average rate of necrosis of the NAC was 5.9%. The main factors of these recurrences were the tumor size > 5 cm and tumor stage > stage II. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> Conservative mastectomy of the nipple-areola complex offers an aesthetic advantage and oncological safety in carefully selected p

关 键 词：Nipple-Sparing Mastectomy Breast Cancer Local Recurrence Necrosis of the Nipple Global Complications 

分 类 号：R73[医药卫生—肿瘤]