Contribution of Colposcopy in the Diagnosis of Precancerous Lesions of the Uterine Cervix at the Douala Gynaeco-Obstetric and Pediatric Hospital, Cameroon  

作　　者：Diane Estelle Modjo Kamdem Alphonse Nyong Ngalame Inna Rakya Robert Tchounzou Darolles Wekam Mwadjie Humphry Tatah Neng Bilkissou Moustapha Julie Batta Patricia Metouom Kamdem Charlotte Nguefack Tchente Emile Mboudou Diane Estelle Modjo Kamdem;Alphonse Nyong Ngalame;Inna Rakya;Robert Tchounzou;Darolles Wekam Mwadjie;Humphry Tatah Neng;Bilkissou Moustapha;Julie Batta;Patricia Metouom Kamdem;Charlotte Nguefack Tchente;Emile Mboudou(Douala Gynaeco-Obstetric and Pediatric Hospital, Douala, Cameroon;Faculty of Health Sciences, University of Buea, Buea, Cameroon;Faculty of Medicine and Biomedical Sciences, University of Garoua, Garoua, Cameroon;Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon;University of Pittsburg Medical Center-Mckeesport, Pittsburg, USA;Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon)

机构地区：[1]Douala Gynaeco-Obstetric and Pediatric Hospital, Douala, Cameroon [2]Faculty of Health Sciences, University of Buea, Buea, Cameroon [3]Faculty of Medicine and Biomedical Sciences, University of Garoua, Garoua, Cameroon [4]Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon [5]University of Pittsburg Medical Center-Mckeesport, Pittsburg, USA [6]Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon

出　　处：《Open Journal of Obstetrics and Gynecology》2022年第10期1031-1041,共11页妇产科期刊（英文）

摘　　要：Introduction: Cervical cancer is a public health problem in Cameroon, due to low screening and late diagnosis. We sought to assess practice of colposcopy at the Douala Gyneco-Obstetric and Pediatric Hospital (DGOPH) in Cameroon and its contribution to the fight against cervical cancer in our context. Method: This is a retrospective cross-sectional study of 99 colposcopies after which 71 exploitable biopsies were retained at the Douala for a period of 1year (December 1, 2019-December 1, 2020). The nomenclature of the French Society of Colposcopy and Cervico-Vaginal Pathology (SFCPCV) was used. Results: Mean age of the participants was 44 years, mostly multiparous (80%). Cytological abnormalities were the main reference pattern. During the examination 22% of colposcopies were found to be normal, 37% of TAG 1-2A, 31% of TAG 2B-C, and 5% suspected of cancer. After histological analysis of biopsies guided by colposcopy, we found 42% (30/71) of Cervical Intraepithelial Neoplasia (CIN) 1, 15.5% (11/71) of CIN 2 - 3, and 24% (17/71) cancer. Upon analysis of the diagnosed CIN1/CIN2-3/Cancers, we noted a concordance with colposcopy in 62% (23/37), 37% (10/27) and 85% (6/7) respectively. Colposcopic performance in the detection of high-grade lesions and above was 36% (26/71), with a sensitivity of 92.86%, specificity 83.33%, PPV 78.79% and NPV 94.59%. Conclusion: Despite the difficult socioeconomic context, colposcopy retains all its importance in the diagnosis of precancerous lesions of the uterine cervix. With the imminent putting in place of a national health policy, the goals 90-70-90 by 2030 of the World Health Organization for the fight against cervical cancer can be achieved in our sub-Saharan African countries.Introduction: Cervical cancer is a public health problem in Cameroon, due to low screening and late diagnosis. We sought to assess practice of colposcopy at the Douala Gyneco-Obstetric and Pediatric Hospital (DGOPH) in Cameroon and its contribution to the fight against cervical cancer in our context. Method: This is a retrospective cross-sectional study of 99 colposcopies after which 71 exploitable biopsies were retained at the Douala for a period of 1year (December 1, 2019-December 1, 2020). The nomenclature of the French Society of Colposcopy and Cervico-Vaginal Pathology (SFCPCV) was used. Results: Mean age of the participants was 44 years, mostly multiparous (80%). Cytological abnormalities were the main reference pattern. During the examination 22% of colposcopies were found to be normal, 37% of TAG 1-2A, 31% of TAG 2B-C, and 5% suspected of cancer. After histological analysis of biopsies guided by colposcopy, we found 42% (30/71) of Cervical Intraepithelial Neoplasia (CIN) 1, 15.5% (11/71) of CIN 2 - 3, and 24% (17/71) cancer. Upon analysis of the diagnosed CIN1/CIN2-3/Cancers, we noted a concordance with colposcopy in 62% (23/37), 37% (10/27) and 85% (6/7) respectively. Colposcopic performance in the detection of high-grade lesions and above was 36% (26/71), with a sensitivity of 92.86%, specificity 83.33%, PPV 78.79% and NPV 94.59%. Conclusion: Despite the difficult socioeconomic context, colposcopy retains all its importance in the diagnosis of precancerous lesions of the uterine cervix. With the imminent putting in place of a national health policy, the goals 90-70-90 by 2030 of the World Health Organization for the fight against cervical cancer can be achieved in our sub-Saharan African countries.

关 键 词：COLPOSCOPY CERVIX DYSPLASIA Cancer DGOPH 

分 类 号：R73[医药卫生—肿瘤]