Ovarian Cancer: Clinical, Therapeutic and Prognostic Aspects at the University Hospital Center of Conakry in Guinea  

作　　者：Abdourahamane Diallo Mamadou Hady Diallo Fatoumata Bamba Diallo Ibrahima Koussy Bah Boubacar Siddy Diallo Ibrahima Sory Balde Telly Sy Namory Keita Abdourahamane Diallo;Mamadou Hady Diallo;Fatoumata Bamba Diallo;Ibrahima Koussy Bah;Boubacar Siddy Diallo;Ibrahima Sory Balde;Telly Sy;Namory Keita(Gynecology-Obstetrics Department, Ignace Deen National Hospital, Conakry, Guinea;Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University of Conakry, Conakry, Guinea;Gynecology-Obstetrics Department, Donka National Hospital, Conakry, Guinea)

机构地区：[1]Gynecology-Obstetrics Department, Ignace Deen National Hospital, Conakry, Guinea [2]Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University of Conakry, Conakry, Guinea [3]Gynecology-Obstetrics Department, Donka National Hospital, Conakry, Guinea

出　　处：《Open Journal of Obstetrics and Gynecology》2023年第12期1985-1993,共9页妇产科期刊（英文）

摘　　要：Background: Ovarian cancer is the seventh most common cancer in women in the world and is the leading cause of death among gynecological cancers. Objective: The objective of this study was to describe the clinical, therapeutic and prognostic aspects of ovarian cancer in the both Gynecology-Obstetrics departments Donka and Ignace Deen of the Conakry University Hospital. Methods: This was a retrospective, descriptive study lasting 12 years from January 1, 2011 to December 31, 2022, covering the files of patients treated for ovarian cancer in the both Gynecology-Obstetrics departments Donka and Ignace Deen. The study focused on the epidemiological, clinical, histological and therapeutic aspects of the disease. Results: In total, 135 files of patients with ovarian cancer were collected out of the 3821 files of gynecological pathologies recorded in the two departments during the study period, either a frequency of 3.5%. Among gynecological and breast cancers, ovarian cancer represented 9.1%. The average age of the patients was 46.3± 17.8 years and the average parity was 4 ± 3. The revealing clinical signs were dominated by pelvic pain (92.6%) and increased abdominal volume (53.3%). The diagnosis of the disease was made mainly at stages III and IV (71.9%). The most common histological type was serous papillary adenocarcinoma (57.0%). Exclusive surgical treatment was performed in 8.1% of patients, surgery combined with chemotherapy in 63.0% of patients and exclusive chemotherapy in 11.1% of patients. After an average follow-up of 42 months, 29 patients out of the 96 operated on were alive (30.2%), 51 had died (53.1%) and 16 patients were lost to follow-up (16.7%). Conclusion: Ovarian cancer is the third most common cancer in both departments. Diagnosis is often late and the prognosis is poor.Background: Ovarian cancer is the seventh most common cancer in women in the world and is the leading cause of death among gynecological cancers. Objective: The objective of this study was to describe the clinical, therapeutic and prognostic aspects of ovarian cancer in the both Gynecology-Obstetrics departments Donka and Ignace Deen of the Conakry University Hospital. Methods: This was a retrospective, descriptive study lasting 12 years from January 1, 2011 to December 31, 2022, covering the files of patients treated for ovarian cancer in the both Gynecology-Obstetrics departments Donka and Ignace Deen. The study focused on the epidemiological, clinical, histological and therapeutic aspects of the disease. Results: In total, 135 files of patients with ovarian cancer were collected out of the 3821 files of gynecological pathologies recorded in the two departments during the study period, either a frequency of 3.5%. Among gynecological and breast cancers, ovarian cancer represented 9.1%. The average age of the patients was 46.3± 17.8 years and the average parity was 4 ± 3. The revealing clinical signs were dominated by pelvic pain (92.6%) and increased abdominal volume (53.3%). The diagnosis of the disease was made mainly at stages III and IV (71.9%). The most common histological type was serous papillary adenocarcinoma (57.0%). Exclusive surgical treatment was performed in 8.1% of patients, surgery combined with chemotherapy in 63.0% of patients and exclusive chemotherapy in 11.1% of patients. After an average follow-up of 42 months, 29 patients out of the 96 operated on were alive (30.2%), 51 had died (53.1%) and 16 patients were lost to follow-up (16.7%). Conclusion: Ovarian cancer is the third most common cancer in both departments. Diagnosis is often late and the prognosis is poor.

关 键 词：Cancer OVARY Ignace Deen Donka 

分 类 号：R73[医药卫生—肿瘤]