Iron-Deficiency Anemia Management in Gynecological Surgery: A Review of Current Evidence and Best Practices  

作　　者：Aline Evangelista Santiago Artur Lima Sendin Víctor Nilo Nogueira Rogério Adão Braga Admilson Lemos Costa Filho Eduardo Batista Cândido Agnaldo Lopes Silva Filho Aline Evangelista Santiago;Artur Lima Sendin;Víctor Nilo Nogueira;Rogério Adão Braga;Admilson Lemos Costa Filho;Eduardo Batista Cândido;Agnaldo Lopes Silva Filho(Department of Gynecology and Obstetrics, Faculty of Medicine, Santo Amaro University (UNISA), So Paulo, Brazil;Department of Gynecology and Obstetrics, Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil;Department of Gynecology and Obstetrics, Faculty of Medicine, So Paulo State University (UNESP), So Paulo, Brazil)

机构地区：[1]Department of Gynecology and Obstetrics, Faculty of Medicine, Santo Amaro University (UNISA), So Paulo, Brazil [2]Department of Gynecology and Obstetrics, Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil [3]Department of Gynecology and Obstetrics, Faculty of Medicine, So Paulo State University (UNESP), So Paulo, Brazil

出　　处：《Open Journal of Obstetrics and Gynecology》2024年第8期1223-1241,共19页妇产科期刊（英文）

摘　　要：Purpose: Due to the high prevalence of iron deficiency anemia in women undergoing gynecological surgeries and its association with worse postoperative results, it is necessary to identify and treat anemia preoperatively. However, although anemia and iron deficiency are significant global health problems, there are still disparities in the recognition and implementation of “Patient Blood Management” (PBM) as a comprehensive approach to mitigating the risks associated with these diseases. The purpose of the study is to review best practices for the treatment of anemia based on the Enhanced Recovery After Surgery (ERAS) protocol and PBM recommendations. Methods: This study reviewed the literature on preoperative iron deficiency anemia in patients undergoing gynecological surgery. We identified references through searches in PubMed using relevant search terms. Results: Among the various strategies used in PBM, perhaps the most important is the early detection and management of anemia. In gynecological surgery, there are several approaches to reducing perioperative blood loss, highlighting the use of gonadotropin-releasing hormone (GnRH) agonists (aGnRh) and antifibrinolytics. Oral and intravenous iron supplementation can be performed in addition to blood transfusion to treat anemia. Conclusion: Addressing preoperative and postoperative anemia through systematic correction, following the guidelines of the ERAS protocol and PBM guidelines, is essential to improving perioperative outcomes in women undergoing gynecological surgery.Purpose: Due to the high prevalence of iron deficiency anemia in women undergoing gynecological surgeries and its association with worse postoperative results, it is necessary to identify and treat anemia preoperatively. However, although anemia and iron deficiency are significant global health problems, there are still disparities in the recognition and implementation of “Patient Blood Management” (PBM) as a comprehensive approach to mitigating the risks associated with these diseases. The purpose of the study is to review best practices for the treatment of anemia based on the Enhanced Recovery After Surgery (ERAS) protocol and PBM recommendations. Methods: This study reviewed the literature on preoperative iron deficiency anemia in patients undergoing gynecological surgery. We identified references through searches in PubMed using relevant search terms. Results: Among the various strategies used in PBM, perhaps the most important is the early detection and management of anemia. In gynecological surgery, there are several approaches to reducing perioperative blood loss, highlighting the use of gonadotropin-releasing hormone (GnRH) agonists (aGnRh) and antifibrinolytics. Oral and intravenous iron supplementation can be performed in addition to blood transfusion to treat anemia. Conclusion: Addressing preoperative and postoperative anemia through systematic correction, following the guidelines of the ERAS protocol and PBM guidelines, is essential to improving perioperative outcomes in women undergoing gynecological surgery.

关 键 词：ANEMIA Gynecological Surgery Iron Supplementation Iron Deficiency 

分 类 号：R73[医药卫生—肿瘤]