Acute Transverse Myelitis in Pregnancy—A Case Report and a Literature Review  

作　　者：Huda Abbas Ali Isa Fatema Hasan Zainab Mohd Al Aswad Naeema Ahmed Abdulkareem Huda Abbas Ali Isa;Fatema Hasan;Zainab Mohd Al Aswad;Naeema Ahmed Abdulkareem(Salmaniya Medical Complex, Manama, Bahrain;Ob Gyn Faculty, Arabian Gulf University, Manama, Bahrain)

机构地区：[1]Salmaniya Medical Complex, Manama, Bahrain [2]Ob Gyn Faculty, Arabian Gulf University, Manama, Bahrain

出　　处：《Open Journal of Obstetrics and Gynecology》2024年第9期1512-1521,共10页妇产科期刊（英文）

摘　　要：Purpose: This case report highlights a rare instance of a 26-week pregnant woman presenting with limb numbness, diagnosed with acute transverse myelitis (ATM) following COVID-19 vaccination. Notably, she tested positive for neuromyelitis optica (NMO) but did not exhibit the typical symptoms of blurred vision. Methods: Data were collected from I Seha in governmental hospitals in Bahrain, providing a comprehensive overview of the patient’s clinical journey. Results: The patient was treated with carbamazepine, steroids, and clexane, leading to the successful delivery of a healthy baby at 34 weeks. However, two years postpartum, she reported new episodes of blurred vision and numbness. Subsequent treatment with Rituximab resulted in significant improvement, with a diagnosis of Devic’s disease established. Conclusion: Acute transverse myelitis is a rare condition, particularly during pregnancy, and in this case, symptoms of Devic’s disease were masked by the absence of blurred vision. This condition predominantly affects females in their 20s during childbearing years and can lead to complications such as premature delivery. Effective management includes steroids and antiepileptic drugs, with clexane playing a crucial role in preventing embolisms. A delivery mode may vary based on obstetric factors, and MRI remains the gold standard for diagnosis. Close follow-up is essential for optimal patient outcomes.Purpose: This case report highlights a rare instance of a 26-week pregnant woman presenting with limb numbness, diagnosed with acute transverse myelitis (ATM) following COVID-19 vaccination. Notably, she tested positive for neuromyelitis optica (NMO) but did not exhibit the typical symptoms of blurred vision. Methods: Data were collected from I Seha in governmental hospitals in Bahrain, providing a comprehensive overview of the patient’s clinical journey. Results: The patient was treated with carbamazepine, steroids, and clexane, leading to the successful delivery of a healthy baby at 34 weeks. However, two years postpartum, she reported new episodes of blurred vision and numbness. Subsequent treatment with Rituximab resulted in significant improvement, with a diagnosis of Devic’s disease established. Conclusion: Acute transverse myelitis is a rare condition, particularly during pregnancy, and in this case, symptoms of Devic’s disease were masked by the absence of blurred vision. This condition predominantly affects females in their 20s during childbearing years and can lead to complications such as premature delivery. Effective management includes steroids and antiepileptic drugs, with clexane playing a crucial role in preventing embolisms. A delivery mode may vary based on obstetric factors, and MRI remains the gold standard for diagnosis. Close follow-up is essential for optimal patient outcomes.

关 键 词：Acute Transverse Myelitis (ATM) COVID-19 Devic’s Syndrome Neuromyelitis Optica (NMO) Obstetric Management of ATM 

分 类 号：R73[医药卫生—肿瘤]