Unilateral Periorbital Oedema with Hypothyroidism and Multinodular Goiter  

作　　者：Blerta Rama Nishant Taneja Nazmije Martinaj Genc Shala Admir Sulovari Naser Gjonbalaj Blerta Rama;Nishant Taneja;Nazmije Martinaj;Genc Shala;Admir Sulovari;Naser Gjonbalaj(Department of Ophthalmology of Prishtina (Kosovo) and Tirana (Albania), Department of Internal Medicine and Rheumatology, De-partment Endocrinology, Radiology, Allergology, Infectiology, American Hospital Pristina, Prishtina, Kosovo)

机构地区：[1]Department of Ophthalmology of Prishtina (Kosovo) and Tirana (Albania), Department of Internal Medicine and Rheumatology, De-partment Endocrinology, Radiology, Allergology, Infectiology, American Hospital Pristina, Prishtina, Kosovo

出　　处：《Open Journal of Ophthalmology》2021年第3期229-239,共11页眼科学期刊（英文）

摘　　要：Thyroid associated ophthalmopathy is an autoimmune disorder which involves orbital and periorbital tissue. The immune-mediated inflammation of the orbital tissues can involve extraocular muscles, orbital connective tissue or orbital fat and periocular soft tissues. Bilateral involvement of thyroid associated orbitopathy is usually asymmetric, but unilateral thyroid associated orbitopathy has been less reported. Periorbital oedema as the only sign with hypothyroidism is uncommon and if present, it is more frequent bilaterally present and no cases are evidenced as unilateral. Pitting oedema in hypothyroidism is rare and can be due to increased capillary permeability, decreased adrenergic tone and increase in serotonin metabolism. Unilateral periorbital and eyelid oedema can associate with various clinical entities, multidisciplinary team is necessary to exclude the concomitant disease, so the patient can immediately be treated with proper therapy. We represent the case of unusually unilateral recurrent periorbital oedema in the period of time for 3 years with stabilized primary hypothyroidism and multinodular goitre.Thyroid associated ophthalmopathy is an autoimmune disorder which involves orbital and periorbital tissue. The immune-mediated inflammation of the orbital tissues can involve extraocular muscles, orbital connective tissue or orbital fat and periocular soft tissues. Bilateral involvement of thyroid associated orbitopathy is usually asymmetric, but unilateral thyroid associated orbitopathy has been less reported. Periorbital oedema as the only sign with hypothyroidism is uncommon and if present, it is more frequent bilaterally present and no cases are evidenced as unilateral. Pitting oedema in hypothyroidism is rare and can be due to increased capillary permeability, decreased adrenergic tone and increase in serotonin metabolism. Unilateral periorbital and eyelid oedema can associate with various clinical entities, multidisciplinary team is necessary to exclude the concomitant disease, so the patient can immediately be treated with proper therapy. We represent the case of unusually unilateral recurrent periorbital oedema in the period of time for 3 years with stabilized primary hypothyroidism and multinodular goitre.

关 键 词：Thyroid Associated Ophthalmopathy HYPOTHYROIDISM Periorbital Oedema 

分 类 号：R73[医药卫生—肿瘤]