A Patient with Malignant Spinal Epidural Lymphoma with Initial Rapidly Aggravating Paraplegia  

作　　者：Taihei Go Yasuaki Iida Hideyuki Aoki Shintaro Tsuge Keiji Hasegawa Yuichiro Yokoyama Akihito Wada Yuri Akishima-Fukasawa Hiroshi Takahashi 

机构地区：[1]Department of Orthopedics, Toho University, Tokyo, Japan

出　　处：《Open Journal of Orthopedics》2017年第3期90-97,共8页矫形学期刊（英文）

摘　　要：We report the case of a 51-year-old female with rapid neurological deterioration as an initial presentation of non-Hodgkin’s lymphoma. Paraplegia occurred suddenly after a 4-day history of weakness and numbness of the lower extremity. MRI revealed a dorsal epidural mass from T10 to T11 that compressed the spinal cord. There was neither bone destruction nor a paravertebral mass. Emergency decompressive laminectomy and tumor resection were performed. Histological analysis of the surgical specimen indicated diffuse large B cell lymphoma. The clinical stage was IV on CT and complete remission was achieved by subsequent chemotherapy. Spinal cord compression occurs in the course of non-Hodgkin’s lymphoma in 0.1% - 6.5% of cases, but this situation usually develops in the late phase with bone destruction and/or a paravertebral mass. Cord compression and especially the severe symptoms such as paraplegia are rare as the initial presentation of lymphoma.We report the case of a 51-year-old female with rapid neurological deterioration as an initial presentation of non-Hodgkin’s lymphoma. Paraplegia occurred suddenly after a 4-day history of weakness and numbness of the lower extremity. MRI revealed a dorsal epidural mass from T10 to T11 that compressed the spinal cord. There was neither bone destruction nor a paravertebral mass. Emergency decompressive laminectomy and tumor resection were performed. Histological analysis of the surgical specimen indicated diffuse large B cell lymphoma. The clinical stage was IV on CT and complete remission was achieved by subsequent chemotherapy. Spinal cord compression occurs in the course of non-Hodgkin’s lymphoma in 0.1% - 6.5% of cases, but this situation usually develops in the late phase with bone destruction and/or a paravertebral mass. Cord compression and especially the severe symptoms such as paraplegia are rare as the initial presentation of lymphoma.

关 键 词：MALIGNANT LYMPHOMA EPIDURAL Mass PARAPLEGIA THORACIC SPINE 

分 类 号：R73[医药卫生—肿瘤]