Osteofibrous Dysplasia-Like Adamantinoma of the Tibia Diagnosed at Age 6 Years Progressing into a Classic Adamantinoma over 39 Years, Reconstruction Performed by a Modified Capanna Technique: A Case Report  

作　　者：G. Ulrich Exner Pascal A. Schai Tobias C. Bühler Michael O. Kurrer Natasha Forster G. Ulrich Exner;Pascal A. Schai;Tobias C. Bühler;Michael O. Kurrer;Natasha Forster(Orthopaedie Zentrum Zurich, Seestrasse, Zurich, Switzerland;Luzerner Kantonsspital Wolhusen Spitalstrasse, Wolhusen, Switzerland;Kantonspital Baden Im Ergel, Baden, Switzerland;Pathologikum Zurich, Switzerland, Zurich, Switzerland;Swissparc AG, Zurich, Switzerland)

机构地区：[1]Orthopaedie Zentrum Zurich, Seestrasse, Zurich, Switzerland [2]Luzerner Kantonsspital Wolhusen Spitalstrasse, Wolhusen, Switzerland [3]Kantonspital Baden Im Ergel, Baden, Switzerland [4]Pathologikum Zurich, Switzerland, Zurich, Switzerland [5]Swissparc AG, Zurich, Switzerland

出　　处：《Open Journal of Orthopedics》2022年第7期335-344,共10页矫形学期刊（英文）

摘　　要：Background: It is generally accepted that there is a spectrum ranging from Osteofibrous Dysplasia (OFD) to Osteofibrous dysplasia-like Adamantinoma (OFD-AD) to “classic” Adamantinoma (AD). However, it is controversial whether OFD may progress into OFD-AD and AD or these pathologic changes reflect sampling issues. We herein report the fifth case of late development of AD from OFD-AD to underline the importance of long-term follow-up. Case: At 6 years bone biopsy of the tibia revealed the diagnosis of OFD-AD, confirmed by repeat biopsies until the age of 18 years. At age 45 years a progressive focal osteolysis was biopsied and showed histologically a classic AD. The affected tibial diaphysis was resected and pasteurized. Reconstruction was performed adapting the “Capanna technique” of inserting the ipsilateral mobilized fibula into the replanted autologous, pasteurized tibial segment as biologic stabilizer. At 1.5 years follow-up, the reconstruction has healed allowing full weight bearing.Background: It is generally accepted that there is a spectrum ranging from Osteofibrous Dysplasia (OFD) to Osteofibrous dysplasia-like Adamantinoma (OFD-AD) to “classic” Adamantinoma (AD). However, it is controversial whether OFD may progress into OFD-AD and AD or these pathologic changes reflect sampling issues. We herein report the fifth case of late development of AD from OFD-AD to underline the importance of long-term follow-up. Case: At 6 years bone biopsy of the tibia revealed the diagnosis of OFD-AD, confirmed by repeat biopsies until the age of 18 years. At age 45 years a progressive focal osteolysis was biopsied and showed histologically a classic AD. The affected tibial diaphysis was resected and pasteurized. Reconstruction was performed adapting the “Capanna technique” of inserting the ipsilateral mobilized fibula into the replanted autologous, pasteurized tibial segment as biologic stabilizer. At 1.5 years follow-up, the reconstruction has healed allowing full weight bearing.

关 键 词：Osteofibrous Dysplasia-Like Adamantinoma TIBIA Classic Adamantinoma Capanna Technique Pasteurized Autograft 

分 类 号：R73[医药卫生—肿瘤]