Early Management of Nephroblastoma: A Single-Center Study in a Sub-Saharan African Country  

作　　者：Abdoul Karim Doumbia Pierre Togo Mariam Maiga Mohamed Elmouloud Cissé Guédiouma Dembélé Oumar Coulibaly Karamoko Sacko Belco Maiga Djeneba Konaté Abdou Diarra Yakaria Coulibaly Fatoumata Léonie Diakité Abdoul Aziz Diakité Boubacar Togo Check Bougadary Traore Adama Bah Abdoul Karim Doumbia;Pierre Togo;Mariam Maiga;Mohamed Elmouloud Cissé;Guédiouma Dembélé;Oumar Coulibaly;Karamoko Sacko;Belco Maiga;Djeneba Konaté;Abdou Diarra;Yakaria Coulibaly;Fatoumata Léonie Diakité;Abdoul Aziz Diakité;Boubacar Togo;Check Bougadary Traore;Adama Bah(Department of Pediatrics at CHU Gabriel Touré, Bamako, Mali;Reference Health Center of the Municipality 6, Bamako, Mali;Pediatric Surgery Department of the Gabriel Touré CHU, Bamako, Mali;Pathological Anatomy and Cytology Department of the “Point G” CHU, Bamako, Mali)

机构地区：[1]Department of Pediatrics at CHU Gabriel Touré, Bamako, Mali [2]Reference Health Center of the Municipality 6, Bamako, Mali [3]Pediatric Surgery Department of the Gabriel Touré CHU, Bamako, Mali [4]Pathological Anatomy and Cytology Department of the “Point G” CHU, Bamako, Mali

出　　处：《Open Journal of Pediatrics》2021年第4期797-803,共7页儿科学期刊（英文）

摘　　要：<strong>Introduction:</strong><span style="font-family:;" "=""><span style="font-family:Verdana;"> Nephroblastoma is the most common renal cancer in pediatrics. The aim of this study was to describe the epidemiological, clinical, histological characteristics and the immediate outcome of patients with nephroblastoma. </span><b><span style="font-family:Verdana;">Methodology:</span></b><span style="font-family:Verdana;"> This was a cross-sectional study of 18 cases of unilateral nephroblastoma, carried out in the pediatric oncology unit (UOP) of the CHU Gabriel Touré from January 2015 to December 2016. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">The mean age of the patients was 33 months old. The sex ratio was 0.63. The average consultation time was 3 months. A case of malformation syndrome (aniridia and mental retardation) had been observed. The main reason for consultation was abdominal mass (100%) associated with deterioration of general condition (44%), pain (44%) and fever (17%). Stage I accounted for 61% and stage II 39%. The postoperative histological classification made it possible </span><span><span style="font-family:Verdana;">to find the high-risk blastematous type (33%), the regressive type of intermediate risk (11%) and the stromal type of intermediate risk (45%). Toxicities (haematological and digestive) were minimal. The 3-year overall survival was 90%. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> This study is characterized by the predominance of stages I and II and the fairly large percentage of histology at intermediate risk. These results are above all the result of multidisciplinary collaboration.</span></span></span><strong>Introduction:</strong><span style="font-family:;" "=""><span style="font-family:Verdana;"> Nephroblastoma is the most common renal cancer in pediatrics. The aim of this study was to describe the epidemiological, clinical, histological characteristics and the immediate outcome of patients with nephroblastoma. </span><b><span style="font-family:Verdana;">Methodology:</span></b><span style="font-family:Verdana;"> This was a cross-sectional study of 18 cases of unilateral nephroblastoma, carried out in the pediatric oncology unit (UOP) of the CHU Gabriel Touré from January 2015 to December 2016. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">The mean age of the patients was 33 months old. The sex ratio was 0.63. The average consultation time was 3 months. A case of malformation syndrome (aniridia and mental retardation) had been observed. The main reason for consultation was abdominal mass (100%) associated with deterioration of general condition (44%), pain (44%) and fever (17%). Stage I accounted for 61% and stage II 39%. The postoperative histological classification made it possible </span><span><span style="font-family:Verdana;">to find the high-risk blastematous type (33%), the regressive type of intermediate risk (11%) and the stromal type of intermediate risk (45%). Toxicities (haematological and digestive) were minimal. The 3-year overall survival was 90%. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> This study is characterized by the predominance of stages I and II and the fairly large percentage of histology at intermediate risk. These results are above all the result of multidisciplinary collaboration.</span></span></span>

关 键 词：Cancer CHILD NEPHROBLASTOMA Diagnosis PROGNOSIS MALI 

分 类 号：R73[医药卫生—肿瘤]