Aspirin plus Pseudoephedrine (Aspirin Complex) for the Treatment of Symptoms of Upper Respiratory Tract Infection  

作　　者：Michael Voelker Ronald Eccles Uwe Gessner 

机构地区：[1]Bayer AG, Leverkusen, Germany [2]Common Cold Centre, Cardiff University, Cardiff, UK

出　　处：《Open Journal of Respiratory Diseases》2017年第1期25-40,共16页呼吸病期刊（英文）

摘　　要：Upper respiratory tract infections or common colds are a multi-symptom disease which is usually symptomatically treated with fixed dose multi-active ingredient medicinal products which are commonly used as non-prescription and over the counter. However, the active ingredients combined require a particular and clinically sound justification. Analgesics and decongestant can be combined to treat simultaneously the prominent symptoms cold-related pain (e.g. headache, muscle aches and pains), fever, inflammationand nasal/sinus congestion. This overview provides a summary of the evidence supporting the combination of acetylsalicylic acid (aspirin) and pseudoephedrine available in the common cold product Aspirin? Complex.Upper respiratory tract infections or common colds are a multi-symptom disease which is usually symptomatically treated with fixed dose multi-active ingredient medicinal products which are commonly used as non-prescription and over the counter. However, the active ingredients combined require a particular and clinically sound justification. Analgesics and decongestant can be combined to treat simultaneously the prominent symptoms cold-related pain (e.g. headache, muscle aches and pains), fever, inflammationand nasal/sinus congestion. This overview provides a summary of the evidence supporting the combination of acetylsalicylic acid (aspirin) and pseudoephedrine available in the common cold product Aspirin? Complex.

关 键 词：ASPIRIN Acetylsalicylic Acid PSEUDOEPHEDRINE Dissolution PHARMACOKINETIC Upper RESPIRATORY TRACT Infection Clinical Studies 

分 类 号：R5[医药卫生—内科学]