Assessment of Anti-Salmonella Activity of Aqueous and Ethanolic Extract of Senna siamae, Used in Traditional Management of Salmonellosis in Benin  

作　　者：Brice Boris Legba Victorien Dougnon Jerrold Agbankpe Kafayath Fabiyi Christelle Lougbegnon Arnaud Soha Césaire Ayena Esther Deguenon Hornel Koudokpon Lamine Baba-Moussa Brice Boris Legba;Victorien Dougnon;Jerrold Agbankpe;Kafayath Fabiyi;Christelle Lougbegnon;Arnaud Soha;Césaire Ayena;Esther Deguenon;Hornel Koudokpon;Lamine Baba-Moussa(Research Unit in Applied Microbiology and Pharmacology of Natural Substances, Research Laboratory in Applied Biology, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Abomey-Calavi, Benin;Laboratory of Biology and Molecular Typing in Microbiology, Faculty of Sciences and Techniques, University of Abomey-Calavi, Abomey-Calavi, Benin)

机构地区：[1]Research Unit in Applied Microbiology and Pharmacology of Natural Substances, Research Laboratory in Applied Biology, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Abomey-Calavi, Benin [2]Laboratory of Biology and Molecular Typing in Microbiology, Faculty of Sciences and Techniques, University of Abomey-Calavi, Abomey-Calavi, Benin

出　　处：《Pharmacology & Pharmacy》2020年第9期226-234,共9页药理与制药（英文）

摘　　要：Recent ethnopharmacological data cited <i><span style="font-family:Verdana;">Senna siamea</span></i><span style="font-family:Verdana;"> as one of the most widely used medicinal plants in the management of salmonellosis in Benin. However,</span><span> </span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">data related to its activity on non-typhoidal Salmonella spp are limited. This study aimed to assess the antibacterial activity of </span><i><span style="font-family:Verdana;">Senna siamea</span></i><span style="font-family:Verdana;"> on multidrug-resistant </span><i><span style="font-family:Verdana;">Salmonella</span></i><span style="font-family:Verdana;">. Ethanolic and aqueous extracts of </span><i><span style="font-family:Verdana;">S. siamea</span></i><span style="font-family:Verdana;"> were tested for their antibacterial activity on four multidrug-resistant </span><i><span style="font-family:Verdana;">Salmonella</span></i><span style="font-family:Verdana;">: </span><i><span style="font-family:Verdana;">Salmonella</span></i><span style="font-family:Verdana;"> Typhimurium ATCC 14028 and three </span><i><span style="font-family:Verdana;">Salmonella </span></i><span style="font-family:Verdana;">spp</span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">. </span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">isolated from animals intended for human consumption in Benin. Well diffusion technique combined with the determination by microdilution of Minimum Bactericidal Concentration (MBC) and Minimum Inhibitory Concentration (MIC) were used for antibacterial testing. From antibacterial testing, inhibition diameters of the extracts</span><i> </i><span style="font-family:Verdana;">ranged from 7 to 11 mm, for the susceptible strains. Colistin (reference antibiotic) was active on all </span><i><span style="font-family:Verdana;">Salmonella spp.</span></i><span style="Recent ethnopharmacological data cited <i><span style="font-family:Verdana;">Senna siamea</span></i><span style="font-family:Verdana;"> as one of the most widely used medicinal plants in the management of salmonellosis in Benin. However,</span><span> </span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">data related to its activity on non-typhoidal Salmonella spp are limited. This study aimed to assess the antibacterial activity of </span><i><span style="font-family:Verdana;">Senna siamea</span></i><span style="font-family:Verdana;"> on multidrug-resistant </span><i><span style="font-family:Verdana;">Salmonella</span></i><span style="font-family:Verdana;">. Ethanolic and aqueous extracts of </span><i><span style="font-family:Verdana;">S. siamea</span></i><span style="font-family:Verdana;"> were tested for their antibacterial activity on four multidrug-resistant </span><i><span style="font-family:Verdana;">Salmonella</span></i><span style="font-family:Verdana;">: </span><i><span style="font-family:Verdana;">Salmonella</span></i><span style="font-family:Verdana;"> Typhimurium ATCC 14028 and three </span><i><span style="font-family:Verdana;">Salmonella </span></i><span style="font-family:Verdana;">spp</span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">. </span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">isolated from animals intended for human consumption in Benin. Well diffusion technique combined with the determination by microdilution of Minimum Bactericidal Concentration (MBC) and Minimum Inhibitory Concentration (MIC) were used for antibacterial testing. From antibacterial testing, inhibition diameters of the extracts</span><i> </i><span style="font-family:Verdana;">ranged from 7 to 11 mm, for the susceptible strains. Colistin (reference antibiotic) was active on all </span><i><span style="font-family:Verdana;">Salmonella spp.</span></i><span style="

关 键 词：Salmonella spp. Senna siamea SALMONELLOSIS MIC 

分 类 号：O17[理学—数学]