Value of Topology Approach to Diagnose of CAD Based on Magnetocardiographic Current Distribution Maps in Difficult-to-Diagnose Patients  

作　　者：I. Chaikovsky L. Stadnyuk A. Verba Yu. Vasetskyi M. Budnyk G. Mjasnikov A. Kazmirchuk A. Lomakovskyi I. Chaikovsky;L. Stadnyuk;A. Verba;Yu. Vasetskyi;M. Budnyk;G. Mjasnikov;A. Kazmirchuk;A. Lomakovskyi(Glushkov Institute of Cybernetics, National Academy of Science, Kiev, Ukraine;Shupyk National Medical Academy of Post-Graduate Education, Kiev, Ukraine;Department of Military Medicine, Ministry of Defense, Kiev, Ukraine;Institute of Electrodynamics, National Academy of Science, Kyiv, Ukraine;National Military Medical Center, Ministry of Defense, Kiev, Ukraine;Strazhesko National Scientific Center of Cardiology, Kiev, Ukraine)

机构地区：[1]Glushkov Institute of Cybernetics, National Academy of Science, Kiev, Ukraine [2]Shupyk National Medical Academy of Post-Graduate Education, Kiev, Ukraine [3]Department of Military Medicine, Ministry of Defense, Kiev, Ukraine [4]Institute of Electrodynamics, National Academy of Science, Kyiv, Ukraine [5]National Military Medical Center, Ministry of Defense, Kiev, Ukraine [6]Strazhesko National Scientific Center of Cardiology, Kiev, Ukraine

出　　处：《World Journal of Cardiovascular Diseases》2016年第7期235-245,共12页心血管病（英文）

摘　　要：Objective: The purpose of this work is to examine the usefulness of the topological approach for analysis of current density maps during ST-T interval in detection of coronary artery disease (CAD) in patients with proved CAD but normal results of routine tests. Materials and Methods: The patient group included 123 patients. Coronary angiography was done due to chest pain. The control group consisted of 124 healthy volunteers. The MCG test was done by 4-channels MCG system installed at unshielded setting. An integral topological index Kideal, consisting of 4 parameters, has been counted. Results and Conclusions: It is shown that Kideal was higher in patient group compared to control one. Sensitivity was 87%, and specificity was 64%. The topological analysis of MCG current density maps is a valuable tool in noninvasive detection of CAD in difficult-to-diagnose patients with uninformative results of routine tests.Objective: The purpose of this work is to examine the usefulness of the topological approach for analysis of current density maps during ST-T interval in detection of coronary artery disease (CAD) in patients with proved CAD but normal results of routine tests. Materials and Methods: The patient group included 123 patients. Coronary angiography was done due to chest pain. The control group consisted of 124 healthy volunteers. The MCG test was done by 4-channels MCG system installed at unshielded setting. An integral topological index Kideal, consisting of 4 parameters, has been counted. Results and Conclusions: It is shown that Kideal was higher in patient group compared to control one. Sensitivity was 87%, and specificity was 64%. The topological analysis of MCG current density maps is a valuable tool in noninvasive detection of CAD in difficult-to-diagnose patients with uninformative results of routine tests.

关 键 词：MAGNETOCARDIOGRAPHY Coronary Artery Disease Current Distribution Difficult-to-Diagnose Patients Topology Parameters 

分 类 号：TP3[自动化与计算机技术—计算机科学与技术]