Managing Heart Failure and Enhancing Quality of Life for Patients with Preserved and Reduced Ejection Fraction  

作　　者：Sherin Mathew Terry Oroszi Sherin Mathew;Terry Oroszi(Department of Pharmacology and Toxicology, Boonshoft School of Medicine, WSU, Fairborn, OH, USA)

机构地区：[1]Department of Pharmacology and Toxicology, Boonshoft School of Medicine, WSU, Fairborn, OH, USA

出　　处：《World Journal of Cardiovascular Diseases》2024年第12期739-756,共18页心血管病(英文)

摘　　要：Heart failure (HF) is a chronic condition characterized by the heart’s inability to pump blood effectively. Hypertension is a frequent contributing factor. The reduced cardiac output leads to fluid accumulation, causing respiratory distress and chest pain. Ejection fraction (EF), a measure of the left ventricle’s pumping capacity, is crucial in HF diagnosis. HF with reduced EF (HFrEF) is defined by an EF below 40%, often caused by coronary artery disease—approximately half of all HF patients present with HFrEF. The remaining cases encompass HF with mid-range EF (40% - 50%) or HF with preserved EF (HFpEF, EF ≥ 50%).Heart failure (HF) is a chronic condition characterized by the heart’s inability to pump blood effectively. Hypertension is a frequent contributing factor. The reduced cardiac output leads to fluid accumulation, causing respiratory distress and chest pain. Ejection fraction (EF), a measure of the left ventricle’s pumping capacity, is crucial in HF diagnosis. HF with reduced EF (HFrEF) is defined by an EF below 40%, often caused by coronary artery disease—approximately half of all HF patients present with HFrEF. The remaining cases encompass HF with mid-range EF (40% - 50%) or HF with preserved EF (HFpEF, EF ≥ 50%).

关 键 词：Heart Failure PATHOPHYSIOLOGY ETIOLOGY Reduced Ejection Fraction Preserved Ejection Fraction REVASCULARIZATION CABG Ventricular Remodeling Myocardial Viability 

分 类 号：X70[环境科学与工程—环境工程]