Specimen Radiography for MRI-Guided Biopsies  

作　　者：Stefanie Woodard Elizabeth Allen Renu Pandit Glenn Irby Shi Wei Yufeng Li Jeong Mi Park Stefanie Woodard;Elizabeth Allen;Renu Pandit;Glenn Irby;Shi Wei;Yufeng Li;Jeong Mi Park(Department of Radiology, The University of Alabama at Birmingham, Birmingham, USA;School of Medicine, The University of Alabama at Birmingham, Birmingham, USA;Department of Anatomic Pathology, The University of Alabama at Birmingham, Birmingham, USA;Department of Medicine, The University of Alabama at Birmingham, Birmingham, USA)

机构地区：[1]Department of Radiology, The University of Alabama at Birmingham, Birmingham, USA [2]School of Medicine, The University of Alabama at Birmingham, Birmingham, USA [3]Department of Anatomic Pathology, The University of Alabama at Birmingham, Birmingham, USA [4]Department of Medicine, The University of Alabama at Birmingham, Birmingham, USA

出　　处：《Open Journal of Radiology》2021年第4期139-150,共12页放射学期刊（英文）

摘　　要：<strong>Background:</strong> Specimen radiography is important for the biopsy of breast microcalcifications, and MRI is limited in the detection of microcalcifications. It is unknown whether or not the presence of microcalcifications on MRI-guided biopsies is significant. <strong>Purpose:</strong> To determine whether specimen radiography of MRI-guided biopsy samples provides any added benefits in tissue assessment. <strong>Materials and Methods:</strong> This is an IRB-approved, HIPPA-compliant retrospective review of MRI-guided biopsy reports whose tissue underwent specimen radiography from 2010 to 2017. Pathology reports were queried to compare samples with and without calcium and reviewed to determine if calcifications correlated with the lesion of interest. If there was a correlation, the original MRI was reviewed. Final pathology reports were also reviewed if excision was performed. <strong>Results:</strong> A total of 889 patients ages 22 - 85 were included with 140 (15.7%, 140/889) containing calcifications. Of 140 specimens, 119 (85.0%, 119/140) cases separated the calcifications. A total of 41 (34.5%, 41/119) were malignant or high-risk lesions/atypia of which 15 (36.6%, 15/41) showed a higher-grade lesion in the specimen containing calcium. Out of these 15, 4 (26.7%, 4/15) were pathologically associated with calcium;however, pathologic diagnosis was not dependent on the presence of calcifications. All 4 were high-risk lesions and none were malignancies. MRI in these cases showed three enhancing masses and one non-mass enhancement. None were upgraded at excision. <strong>Conclusion:</strong> The presence of microcalcifications on MRI-guided biopsies does not aid in tissue assessment and does not impact pathologic diagnosis. Specimen radiography provides no added benefits in the setting of MRI-guided biopsies.<strong>Background:</strong> Specimen radiography is important for the biopsy of breast microcalcifications, and MRI is limited in the detection of microcalcifications. It is unknown whether or not the presence of microcalcifications on MRI-guided biopsies is significant. <strong>Purpose:</strong> To determine whether specimen radiography of MRI-guided biopsy samples provides any added benefits in tissue assessment. <strong>Materials and Methods:</strong> This is an IRB-approved, HIPPA-compliant retrospective review of MRI-guided biopsy reports whose tissue underwent specimen radiography from 2010 to 2017. Pathology reports were queried to compare samples with and without calcium and reviewed to determine if calcifications correlated with the lesion of interest. If there was a correlation, the original MRI was reviewed. Final pathology reports were also reviewed if excision was performed. <strong>Results:</strong> A total of 889 patients ages 22 - 85 were included with 140 (15.7%, 140/889) containing calcifications. Of 140 specimens, 119 (85.0%, 119/140) cases separated the calcifications. A total of 41 (34.5%, 41/119) were malignant or high-risk lesions/atypia of which 15 (36.6%, 15/41) showed a higher-grade lesion in the specimen containing calcium. Out of these 15, 4 (26.7%, 4/15) were pathologically associated with calcium;however, pathologic diagnosis was not dependent on the presence of calcifications. All 4 were high-risk lesions and none were malignancies. MRI in these cases showed three enhancing masses and one non-mass enhancement. None were upgraded at excision. <strong>Conclusion:</strong> The presence of microcalcifications on MRI-guided biopsies does not aid in tissue assessment and does not impact pathologic diagnosis. Specimen radiography provides no added benefits in the setting of MRI-guided biopsies.

关 键 词：MRI-Guided Breast Biopsy Specimen Radiography MICROCALCIFICATIONS High-Risk Lesion Breast Cancer Upgrade 

分 类 号：R73[医药卫生—肿瘤]