Transposable elements in <i>Escherichia coli</i>antimicrobial resistance  

作　　者：Archana Iyer Elie Barbour Esam Azhar Alaaeddin Ali El Salabi Hani Mutlak A. Hassan Ishtiaq Qadri Adeel Chaudhary Adel Abuzenadah Taha Kumosani Ghazi Damanhouri Maha Alawi Tarek Na’was Afif M. Abdel Nour Steve Harakeh 

机构地区：[1]Department of Animal and Veterinary Sciences, American University of Beirut, Beirut, Lebanon [2]Department of Biochemistry, King Abdulaziz University, Jeddah, KSA [3]Infection Control and Antimicrobial Drug Resistance, University of Benghazi, Benghazi, Libya [4]Infection Control and Environmental Health Unit, King Abdulaziz University Hospital, King Abdulaziz University, Jeddah, KSA [5]King Fahd Medical Research Center, King Abdulaziz University, Jeddah, KSA [6]Lebanese American University, Beirut, Lebanon [7]Special Infectious Agents Unit—Biosafety Level 3, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, KSA

出　　处：《Advances in Bioscience and Biotechnology》2013年第3期415-423,共9页生命科学与技术进展（英文）

摘　　要：Transposable elements are capable of switching their positions on the genome thereby causing gene arrangements and contributing to genome evolution. The aim of this review is to specifically discuss the role of transposable elements in transferring antimicrobial resistance genes in E. coli, thus contributing to increase in virulence and conferring the possibility of multidrug resistance. Different types of transposable elements such as transposons and integrons and their profound influence on E. coli antimicrobial resistance are the focus of this review.Transposable elements are capable of switching their positions on the genome thereby causing gene arrangements and contributing to genome evolution. The aim of this review is to specifically discuss the role of transposable elements in transferring antimicrobial resistance genes in E. coli, thus contributing to increase in virulence and conferring the possibility of multidrug resistance. Different types of transposable elements such as transposons and integrons and their profound influence on E. coli antimicrobial resistance are the focus of this review.

关 键 词：TRANSPOSABLE Elements E. COLI ANTIMICROBIAL Resistance INTEGRONS 

分 类 号：R73[医药卫生—肿瘤]