<i>Borrelia</i><i>burgdorferi</i>: Cell Biology and Clinical Manifestations in Latent Chronic Lyme  

作　　者：Aaron J. Smith John Oertle Dino Prato 

机构地区：[1]Envita, Scottsdale, AZ, USA

出　　处：《Open Journal of Medical Microbiology》2014年第4期210-223,共14页医学微生物学（英文）

摘　　要：Chronic Lyme disease is predicated by an infection with Borrelia burgdorferi via tick vector. B. burgdorferi has been extensively researched with regard to its genome and cell biology. There are many unique characteristics to the bacteria itself;however, serological diagnostics and diagnosis based on symptoms can be complicated and potentially misleading. Other promising diagnostics were also evaluated in this review. Treatment of the chronic Lyme disease can be complicated and at times ineffective. The purpose of this review is to examine B. burgdorferi from a biological and clinical perspective.Chronic Lyme disease is predicated by an infection with Borrelia burgdorferi via tick vector. B. burgdorferi has been extensively researched with regard to its genome and cell biology. There are many unique characteristics to the bacteria itself;however, serological diagnostics and diagnosis based on symptoms can be complicated and potentially misleading. Other promising diagnostics were also evaluated in this review. Treatment of the chronic Lyme disease can be complicated and at times ineffective. The purpose of this review is to examine B. burgdorferi from a biological and clinical perspective.

关 键 词：LYME Disease BORRELIA BURGDORFERI Genome Cellular Process Epidemiology CD57 C4a Diagnostics Treatment 

分 类 号：R5[医药卫生—内科学]