Detection and Quantification of Anti-Inflammatory Cytokine in Sera and Urine of Sudanese Patients Infected with Schistosoma haematobium  

作　　者：A. Hammad Manahil Nouri Abdelbagi Alfadil H. A. Musa M. A. Osman A. Bashir Nawal Eltayeb Omer Yasir Hassan A. Alfarazdeg A. Mustafa A. Hammad;Manahil Nouri;Abdelbagi Alfadil;H. A. Musa;M. A. Osman;A. Bashir;Nawal Eltayeb Omer;Yasir Hassan;A. Alfarazdeg;A. Mustafa(Department of Parasitology, National Ribat University, Khartoum, Sudan;Department of Community Medicine, Al Neelain University, Khartoum, Sudan;Department of Immunology, National Ribat University, Khartoum, Sudan;Department of Microbiology, National Ribat University, Khartoum, Sudan;Department of Microbiology, University of Bacht Elruda, Eldeum, Sudan;Department of Microbiology, Khartoum University, Khartoum, Sudan;Department of Pathology, Khartoum College of Medical Sciences, Khartoum, Sudan;Sudan Medical Specialization Board, Khartoum, Sudan;Department of Biochemistry, Khartoum University, Khartoum, Sudan;Soba Hospital, Khartoum University, Khartoum, Sudan)

机构地区：[1]Department of Parasitology, National Ribat University, Khartoum, Sudan [2]Department of Community Medicine, Al Neelain University, Khartoum, Sudan [3]Department of Immunology, National Ribat University, Khartoum, Sudan [4]Department of Microbiology, National Ribat University, Khartoum, Sudan [5]Department of Microbiology, University of Bacht Elruda, Eldeum, Sudan [6]Department of Microbiology, Khartoum University, Khartoum, Sudan [7]Department of Pathology, Khartoum College of Medical Sciences, Khartoum, Sudan [8]Sudan Medical Specialization Board, Khartoum, Sudan [9]Department of Biochemistry, Khartoum University, Khartoum, Sudan [10]Soba Hospital, Khartoum University, Khartoum, Sudan

出　　处：《Open Journal of Medical Microbiology》2016年第1期32-41,共10页医学微生物学（英文）

摘　　要：Cytokines have been in focus of scientific in for more than decade now. Analyzing their expression has enabled a better understanding of pathogenesis of various diseases. Moreover, they are now for beyond their stage when they were of interest for pathophysiological research. In the present study, we used an assay to anti-inflammatory cytokines. One hundred and thirty sera and urine from egg positive individuals and 42 samples of healthy individuals in Eldeum locality—an endemic area of S. haematobum and 28 healthy individuals from non-endemic area were tested. Concentration of IL5 and IL10 is reverse. IL5 is low in serum but high in urine before treatment and high in serum and low in urine after treatment. IL10 is high in serum, low in urine before treatment and low in serum, high in urine after treatment.Cytokines have been in focus of scientific in for more than decade now. Analyzing their expression has enabled a better understanding of pathogenesis of various diseases. Moreover, they are now for beyond their stage when they were of interest for pathophysiological research. In the present study, we used an assay to anti-inflammatory cytokines. One hundred and thirty sera and urine from egg positive individuals and 42 samples of healthy individuals in Eldeum locality—an endemic area of S. haematobum and 28 healthy individuals from non-endemic area were tested. Concentration of IL5 and IL10 is reverse. IL5 is low in serum but high in urine before treatment and high in serum and low in urine after treatment. IL10 is high in serum, low in urine before treatment and low in serum, high in urine after treatment.

关 键 词：Schistosoma haematobum INTERLEUKIN ELISA 

分 类 号：R73[医药卫生—肿瘤]