Solvent-Free Synthesis of Carboxylic Acids and Amide Analogs of CAPE(Caffeic Acid Phenethyl Ester)under Infrared Irradiation Conditions  

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作  者:Pablo A.Martínez-Soriano Jose R.Macías-Perez Ana Maria Velazquez Brigida del Carmen Camacho-Enriquez Gustavo Pretelin-Castillo Monica B.Ruiz-Sanchez Victor H.Abrego-Reyes Saul Villa-Trevino Enrique Angeles 

机构地区:[1]Laboratorio de Quimica Medicinal y Teorica,Departamento de Ciencias Quimicas,FES Cuautitlan,Universidad Nacional Autonoma de Mexico,Cuautitlan Izcalli,Mexico [2]Departamento de Biologia celular,Centro de Investigacion y Estudios Avanzados,Instituto Politecnico Nacional,Mexico,D.F.,Mexico [3]Qsar Analytics S.A.de C.V.Ciudad Satelite,Naucalpan de Juarez,Mexico

出  处:《Green and Sustainable Chemistry》2015年第2期81-91,共11页绿色与可持续化学(英文)

基  金:PAPIIT/UNAM Projects No.IN200614 and IT202015 and project PIAPI VC02 for partially supporting this work;a part of the Project Catedra:Diseno de Sustancias Bioactivas of FESC-UNAM-2012.

摘  要:A convenient and easy method is described for the formation of carboxamides from carboxylic acids and primary amines in solventless conditions using infrared (IR) light. Thus, under IR light, cinnamic acid derivatives and amines can produce yields ranging from 50% to 85% of the resulting amide.A convenient and easy method is described for the formation of carboxamides from carboxylic acids and primary amines in solventless conditions using infrared (IR) light. Thus, under IR light, cinnamic acid derivatives and amines can produce yields ranging from 50% to 85% of the resulting amide.

关 键 词:AMIDES Carboxylic Acids Amines Infrared Light SOLVENTLESS CAPE CAPA Cinnamic Acid Analogs 

分 类 号:O6[理学—化学]

 

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