Synthetic Studies of Naphtho[2,3-b]furan Moiety Present in Diverse Bioactive Natural Products  

作　　者：Bidyut Kumar Senapati Dipakranjan Mal 

机构地区：[1]Department of Chemistry, Prabhat Kumar College, Contai, India [2]Department of Chemistry, Indian Institute of Technology, Kharagpur, India

出　　处：《International Journal of Organic Chemistry》2015年第2期63-74,共12页有机化学国际期刊（英文）

摘　　要：The preparation of several functionalized furan derivatives and attempts to transform them into a derivative containing 6H-furo[3,4-b]furanone skeleton towards the construction of naphtho[2,3-b] furan are described. Attempted Pummerer reaction of a furan sulfoxide derivative produced four interesting furan derivatives. Base promoted annulation between methyl 2-(phenylsulfinylmethyl)-3-furoate and 2-cyclohexenone proceeded to give dihydro naphtho[2,3-b]furanone derivative in a regiospecific manner.The preparation of several functionalized furan derivatives and attempts to transform them into a derivative containing 6H-furo[3,4-b]furanone skeleton towards the construction of naphtho[2,3-b] furan are described. Attempted Pummerer reaction of a furan sulfoxide derivative produced four interesting furan derivatives. Base promoted annulation between methyl 2-(phenylsulfinylmethyl)-3-furoate and 2-cyclohexenone proceeded to give dihydro naphtho[2,3-b]furanone derivative in a regiospecific manner.

关 键 词：6H-Furo[3 4-b]furanone Naphtho[2 3-b]furan INTRAMOLECULAR Pummerer Reaction Desulfanylation LACTONIZATION 

分 类 号：O6[理学—化学]