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financial supports for this work are provided by the National Natural Science Foundation of China(Nos.21871160,21672121,22071130)。
An N-heterocyclic carbene(NHC)catalyzed enantioselective cyclisation and trifluoromethylation of olefins with cinnamaldehydes via radical relay cross-coupling in the presence of Togni reagent is reported andδ-lactone...
supported by the National Key Research and Development Program of China(No.2022YFF0709803);Natural Science Foundation of Beijing Municipality(No.2202041);the High Performance Computing Platform of Beijing University of Chemical Technology(BUCT).
The reductive lactonization strategy provides an efficient access to diastereoenriched polycyclicγ-lactones.However,it is still a formidable challenge to develop an efficient and versatile protocol with excellent lev...
supported by the Fujian Province Natural Science Foundation (2023J01294);the Natural Science Basic Research Program of Shaanxi (2023-JC-YB-088);the National Natural Science Foundation of China (21501133, 22371067);the China Hunan Provincial Science&Technology Department (2020RC3020, 2021JJ20021,2023JJ40119)。
Dye molecules often change colors(so-called “chromism”) according to the environment variation. However, they are rarely induced by a catalytic amount of cavity. Through encapsulation in the cavity of a porous coord...
We thank the National Key Research and Development Program of China(2021YFF0701700);the National Natural Science Foundation of China(21971252,21991122,22271181);the Science and Technology Commission of Shanghai Municipality(22ZR1423600)for financial support.
Due to its unique electronic properties,the difluoromethylene group(CF2)has served as a valuable unity in the design of biologically active molecules.Sinceγ-lactones display a broad range of biological properties,α,...
supported by the National Natural Science Foundation of China(21502086);the Natural Science Foundation of Fujian Province(2019J01744);the Key Project of Foundation of Fujian Province(2020J02044);the Natural Science Foundation of Zhangzhou City(ZZ2021J13)。
Direct functionalization of inert C(sp^(3))–H bonds in pharmaceutically significant compounds is very important in modern synthetic organic chemistry.In this article,we disclose a practical and efficient method for t...
supported by the National Fund of Science,Technology and Innovation (FONACIT) (Grant N°201300288)within the framework of the project PCP France-Venezuela;by the CDCHTA-ULA (Grant N°C-1935-15-08-ED).
From aerial parts of Austroeupatorium inulifolium was isolated the ent-nor-furano triol labdane austroeupatol 1.The compound 1 was treated with IBX showing an unexpected selectivity at the potentially oxidizable sites...
Supported by the National Natural Science Foundation of China(No.21672203).
A desymmetrization approach for the synthesis of the A-B-C tricycle intermediate of iso-merrilactone A was described. The key steps of this synthesis to efficiently access the tetracyclic Illicium sesquiterpenes core ...
Herein, we report a novel synthesis of 1,3-oxazin-6-ones from enamides with CO2 through C--H carboxylation and one-pot cyclization. This transition-metal-free and redox-neutral process features broad substrate scope, ...
financial support from National Natural Science Foundation of China(NSFC,Nos.21302177,21672049 and 21672030)
An unusual formal oxy transposition of vinylogous β-silyloxy-cyclobutanone 1(a 1,5-difunctionalized substrate) under mild acidic conditions(aqueous HF in CH3CN at 0℃) to the decalinic y-lactone 2 was described.A...
The preparation of several functionalized furan derivatives and attempts to transform them into a derivative containing 6H-furo[3,4-b]furanone skeleton towards the construction of naphtho[2,3-b] furan are described. A...