Synthesis of A-B-C-ring Tricyclic Core of iso-Merrilactone A  

作　　者：TONG Jie LIU Chang WANG Bo 

机构地区：[1]CAS Key Laboratory of High-Performance Synthetic Rubber and Its Composite Materials,Key Laboratory of Green Chemistry and Process of Jilin Province,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun 130022,P.R.China [2]University of Chinese Academy of Sciences,Beijing 100049,P.R.China [3]University of Science and Technology of China,Hefei 230026,P.R.China

出　　处：《Chemical Research in Chinese Universities》2019年第5期817-822,共6页高等学校化学研究（英文版）

基　　金：Supported by the National Natural Science Foundation of China(No.21672203).

摘　　要：A desymmetrization approach for the synthesis of the A-B-C tricycle intermediate of iso-merrilactone A was described. The key steps of this synthesis to efficiently access the tetracyclic Illicium sesquiterpenes core included an intramolecular aldol cyclization and an oxidative lactonization reaction. A novel Au catalyzed hydrolytic cyclorearrangement cascade reaction was explored in the initial stage.

关 键 词：SESQUITERPENE Regio-isomer Cyclorearrangement LACTONIZATION 

分 类 号：O6[理学—化学]