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作 者:Saqer Al Mualla Noura Salim Salman Salma Saeed Ns. Nasreen Abdelatif Mohamed Kanjou Gabriel Molina de Olyveira Pierre Basmaji Antônio Carlos Guastaldi Saqer Al Mualla;Noura Salim Salman;Salma Saeed;Ns. Nasreen Abdelatif;Mohamed Kanjou;Gabriel Molina de Olyveira;Pierre Basmaji;Antônio Carlos Guastaldi(Qassimi Hospital, GEM International, Sharjah, United Arab Emirates;Innovatecs-Biotechnology Research and Development, So Carlos, Brazil;UNESP-IQ-Physical Chemistry Department, Araraquara, Brazil)
机构地区:[1]Qassimi Hospital, GEM International, Sharjah, United Arab Emirates [2]Innovatecs-Biotechnology Research and Development, So Carlos, Brazil [3]UNESP-IQ-Physical Chemistry Department, Araraquara, Brazil
出 处:《Journal of Biomaterials and Nanobiotechnology》2024年第3期39-50,共12页生物材料与纳米技术(英文)
摘 要:Bacterial cellulose (BC) is a versatile biomaterial with unique properties that make it promising for various biomedical applications, including wound healing. The extracellular matrix (ECM) plays a crucial role in wound healing, providing a structural scaffold and signaling cues for cell migration and proliferation. This study investigates the potential of BC as a scaffold for ECM production and its effect on in vivo wound healing. In this work, the bacterial cellulose fermentation process is modified by the addition of Green Propolis and Usnic acid to the culture medium and natural materials before the bacteria are inoculated. In vivo behaviour using natural membranes for regenerative medicine is presented and it is in edit. Overall, our findings demonstrate the potential of BC as a scaffold for ECM production and its beneficial effects on in vivo wound healing. BC-based dressings may offer a novel approach to promoting wound healing and tissue regeneration in clinical settings. Further studies are warranted to optimize BC-based therapies and explore their full potential in regenerative medicine.Bacterial cellulose (BC) is a versatile biomaterial with unique properties that make it promising for various biomedical applications, including wound healing. The extracellular matrix (ECM) plays a crucial role in wound healing, providing a structural scaffold and signaling cues for cell migration and proliferation. This study investigates the potential of BC as a scaffold for ECM production and its effect on in vivo wound healing. In this work, the bacterial cellulose fermentation process is modified by the addition of Green Propolis and Usnic acid to the culture medium and natural materials before the bacteria are inoculated. In vivo behaviour using natural membranes for regenerative medicine is presented and it is in edit. Overall, our findings demonstrate the potential of BC as a scaffold for ECM production and its beneficial effects on in vivo wound healing. BC-based dressings may offer a novel approach to promoting wound healing and tissue regeneration in clinical settings. Further studies are warranted to optimize BC-based therapies and explore their full potential in regenerative medicine.
关 键 词:Bacterial Cellulose BIOMATERIALS NANOMEDICINE Wound Healing Green Propolis and Usnic Acid
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