Environmental Risk of Atrazine (Herbicide) to Brain, Gills and Liver Tissues of Fish <i>Ctenopharyngodon idella</i>(Valenciennes, 1844)  

作　　者：Waqar Ahmad Aamir Sultan Sahibzada Muhammad Haseeb Jan Aamir Ali Ihtisham Ur Rahman Hazrat Usman Ahmad Sher Naqash Khan Suleman   Zahid Khan Ahsan Khan Waqar Ahmad;Aamir Sultan;Sahibzada Muhammad Haseeb Jan;Aamir Ali;Ihtisham Ur Rahman;Hazrat Usman;Ahmad Sher;Naqash Khan;Suleman ;;Zahid Khan;Ahsan Khan(Department of Zoology, University of Swabi, Anbar, Swabi, Khyber Pakhtunkhwa, Pakistan;Department of Zoology, University of Peshawar, Khyber Pakhtunkhwa, Pakistan)

机构地区：[1]Department of Zoology, University of Swabi, Anbar, Swabi, Khyber Pakhtunkhwa, Pakistan [2]Department of Zoology, University of Peshawar, Khyber Pakhtunkhwa, Pakistan

出　　处：《Journal of Geoscience and Environment Protection》2021年第2期1-16,共16页地球科学和环境保护期刊（英文）

摘　　要：The current study investigates the toxic effects of acute dose of an endocrine disruptor atrazine on Grass carp (<em>Ctenepharyngodon idella</em>) using histopathological changes as biomarkers. Histopathology is promising field for research in aquatic toxicology, in this manner vital organs;brain, gills, and liver tissues were inspected histological after exposing to sublethal groupings of atrazine 0.025 and 0.03 μl/L for 3, 6, 9, 12 and 15 days individually with equal untreated control group. Against various doses, rapid movements, gulping of air and jumping of fish to scat from toxic medium were noticed. Various severe (+++) morphological modifications in tissue were documented in comparison with control group comprised of degenerated neurons, vacuolization, inflammatory cells infiltration and neural necrosis in brain tissue. The most well-known gills tissue alteration at all concentrations of atrazine was epithelial hyperplasia, desquamation, epithelial lifting and smaller aneurism while hepatic injuries were described by overcast expanding of hepatocytes esteemed as cloudy swelling of hepatocytes followed by karyolysis, karyohexis and dilation of sinusoids which shows that atrazine introduction upgraded the toxicosis impacts with the increase concentration, influenced the strength of the fish, inferable from histological inconsistencies.The current study investigates the toxic effects of acute dose of an endocrine disruptor atrazine on Grass carp (<em>Ctenepharyngodon idella</em>) using histopathological changes as biomarkers. Histopathology is promising field for research in aquatic toxicology, in this manner vital organs;brain, gills, and liver tissues were inspected histological after exposing to sublethal groupings of atrazine 0.025 and 0.03 μl/L for 3, 6, 9, 12 and 15 days individually with equal untreated control group. Against various doses, rapid movements, gulping of air and jumping of fish to scat from toxic medium were noticed. Various severe (+++) morphological modifications in tissue were documented in comparison with control group comprised of degenerated neurons, vacuolization, inflammatory cells infiltration and neural necrosis in brain tissue. The most well-known gills tissue alteration at all concentrations of atrazine was epithelial hyperplasia, desquamation, epithelial lifting and smaller aneurism while hepatic injuries were described by overcast expanding of hepatocytes esteemed as cloudy swelling of hepatocytes followed by karyolysis, karyohexis and dilation of sinusoids which shows that atrazine introduction upgraded the toxicosis impacts with the increase concentration, influenced the strength of the fish, inferable from histological inconsistencies.

关 键 词：HISTOPATHOLOGICAL Toxicological BRAIN GILLS Liver 

分 类 号：R73[医药卫生—肿瘤]