New Records of Microcystins in Some Bulgarian Water Bodies of Health and Conservational Importance  

作　　者：Vera Pavlova Maya Stoyneva Vesela Georgieva Desislav Donchev Lisa Spoof Jussi Meriluoto Zlatka Bratanova Irina Karadjova 

机构地区：[1]National Centre of Public Health and Analyses,Sofia,Bulgaria [2]Department Botany,Faculty of Biology,Sofia University“St.Kliment Ohridski”,Sofia,Bulgaria [3]Team Consult Ltd.,Sofia,Bulgaria [4]Department of Biochemistry and Pharmacy,Abo Akademi University,Turku,Finland [5]Faculty of Chemistry and Pharmacy,Sofia University“St.Kliment Ohridski”,Sofia,Bulgaria

出　　处：《Journal of Water Resource and Protection》2014年第5期446-453,共8页水资源与保护（英文）

基　　金：financial support of MESY scientific projects DDVU-02/77 and DFNI-T01/5 NANOSORBLAB.

摘　　要：Microcystins cause acute hepatotoxicity and chronic liver tumor promotion. This study presents the results of HPLC DAD analyses and their LC-MS confirmation of samples from five Bulgarian water bodies (reservoirs Stoudena, Pchelina, Bistritsa and lakes Dourankoulak, Vaya). The total concentration of microcystins in water samples ranged from 0.1 to 26.5 μg/l. The amount of microcystins in the biomasses ranged from 11.4 to 49.6 μg/g (d.w.). The high percent of positive samples in which the most toxic microcystin-LR is recorded, can serve as a strong alarm for the necessity of a serious study and relevant discussion of the problem with responsible authorities at national level.Microcystins cause acute hepatotoxicity and chronic liver tumor promotion. This study presents the results of HPLC DAD analyses and their LC-MS confirmation of samples from five Bulgarian water bodies (reservoirs Stoudena, Pchelina, Bistritsa and lakes Dourankoulak, Vaya). The total concentration of microcystins in water samples ranged from 0.1 to 26.5 μg/l. The amount of microcystins in the biomasses ranged from 11.4 to 49.6 μg/g (d.w.). The high percent of positive samples in which the most toxic microcystin-LR is recorded, can serve as a strong alarm for the necessity of a serious study and relevant discussion of the problem with responsible authorities at national level.

关 键 词：CYANOBACTERIA CYANOTOXINS MICROCYSTINS 

分 类 号：R73[医药卫生—肿瘤]