国家自然科学基金(s20375010)

作品数:7被引量:18H指数:3
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相关作者:杨更亮张少军钱训郑振山陈勇达更多>>
相关机构:河北大学中国科学院河北省农林科学院更多>>
相关期刊:《分析化学》《Science Bulletin》《色谱》《河北农业大学学报》更多>>
相关主题:整体柱土壤阳离子盐酸雷尼替丁柱切换更多>>
相关领域:医药卫生理学农业科学环境科学与工程更多>>
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Design and Synthesis of α, β-Epoxyketones as New Anticancer Agents被引量:3
《Chinese Journal of Chemistry》2011年第4期757-764,共8页马正月 张兴华 王士奎 何洋 杨更亮 李蓓蕾 杨俊杰 鲁悦娟 孙杰威 
Project supported by the National Natural Science Foundation of China (Nos. 20375010, 20675084), the Hebei Province Programs for Science and Technology Development (Nos. 06276479B, 07276407D), Key Laboratory for Pharmaceutical Quality Control of Hebei Province Fund (No. 09265631 D-14) and Hebei University Found (No. 2010Q33).
As epoxy functional group has high anticancer activity, α, β-epoxyketones were designed and synthesized as new anticancer agents, and their structures were confirmed by UV, 1H NMR, IR, MS technigeces and elemental a...
关键词:α β-epoxyketones thiochromanones anticancer activity Darzens condensation reaction 
Investigation of biomembrane-drug interactions of different biomembranes by capillary electrophoresis被引量:1
《Chinese Science Bulletin》2009年第12期2033-2037,共5页WEI ChunLiang YANG GengLiang SHANG Chuang GUO LanDi JIA MiaoHui 
Supported by the National Natural Science Foundation of China(Grant Nos.20375010,and20675084);Program for Science and Technology Development of Hebei Province(Grant Nos.06276479B and07276407D);"Bai Ren Project"of Chinese Academy of Sciences
Biomembrane-coated capillaries are prepared by coating different kinds of biomembranes including mice red cell membrane, human red cell membrane and S-180 cell membrane on the inner surface of the capillary, respectiv...
关键词:药物相互作用 生物膜量 毛细管电泳 人红细胞膜 毛细血管 保留因子 pH值 内表面 
胶束电动毛细管色谱法测定硫酸多粘菌素E药物中的多粘菌素E1和E2被引量:4
《色谱》2009年第6期860-863,共4页闫永娜 王利娟 杨更亮 侯文欣 张巧霞 
国家自然科学基金项目(Nos.20375010,20675084);河北省科技攻关项目(Nos.06276479D,07276407D);河北省教育厅项目(No.Z2007225)
采用胶束电动毛细管色谱法(MECC)对硫酸多粘菌素E药物中的主要成分多粘菌素E1和E2进行了分离,并测定了多粘菌素E1、E2的含量。分别考察了电泳电压、表面活性剂种类、Brij-35(月桂醇聚氧乙烯醚)浓度、乙腈含量、磷酸盐缓冲液的pH值、氯...
关键词:胶束电动毛细管色谱 多粘菌素E1 多粘菌素E2 硫酸多粘菌素E 
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