国家自然科学基金(s30770761)

作品数:1被引量:4H指数:1
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相关期刊:《Science China(Life Sciences)》更多>>
相关主题:DOMAINRELATEDN-TERMINALHUNTINGTINAGGREGATES更多>>
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Essential sequence of the N-terminal cytoplasmic localization-related domain of huntingtin and its effect on huntingtin aggregates被引量:4
《Science China(Life Sciences)》2011年第4期342-350,共9页YAN YaPing PENG DanTao TIAN Jun CHI JingWei TAN JieQiong YIN XinZhen PU JiaLi XIA Kun ZHANG BaoRong 
supported by the National Natural Science Foundation of China(Grant Nos.30770761 and 30971000)
Huntington's disease (HD) is caused by abnormal CAG repeat expansion in the 5'-end of the Huntingtin (HTT) gene. In addition to the canonical C-terminal full-length huntingtin (htt) nuclear export signal, a cy...
关键词:HUNTINGTIN AGGREGATES cytoplasmic localization related domain mitochondria POLYGLUTAMINE 
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