国家自然科学基金(30711120570)

作品数：2被引量：5H指数：2
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Nampt is involved in DNA double-strand break repair被引量：2
《Chinese Journal of Cancer》2012年第8期392-398,共7页Bingtao Zhu Xiaoli Deng Yifan Sun Lin Bai Zhikai Xiahou Yusheng Cong Xingzhi Xu 
was supported by the National Natural Science Foundation of China (No.31130017, 31071190, and 30711120570);the 973 project 2010CB911904;Funding Project for Academic Human Resources Development in Institutions of Higher Learning Under the Jurisdiction of Beijing Municipality (No. PHR20110508) to XX;the 973 project 2012CB911203 to YSC
DNA double-strand break(DSB) is the most severe form of DNA damage,which is repaired mainly through high-fidelity homologous recombination(HR) or error-prone non-homologous end joining(NHEJ).Defects in the DNA damage ...
关键词：DNA双链断裂 断裂修复 人成纤维细胞 小分子干扰RNA 非同源末端连接 DNA损伤 细胞衰老 siRNA 
Serine/threonine protein phosphatases in DNA damage response被引量：3
《Chinese Science Bulletin》2011年第30期3122-3131,共10页LIU Bo XU XingZhi 
supported by the startup fund from Capital Normal University;the National Natural Science Foundation of China (30570371, 90608014, 30711120570 and 31071190);the Program for New Century Excellent Talents in University (NCET-06-0187);Beijing Natural Science Foundation Program and Scientific Research Key Program of Beijing Municipal Commission of Education (KZ200810028014);the National Basic Research Program of China (2010CB911904);Funding Project for Academic Human Resources Development in Institutions of Higher Learning under the Jurisdiction of Beijing Municipality (PHR20110508) to XU XingZhi
DNA damage response (DDR) is among the most important of the mechanisms that maintain genome stability which, when destabilized, predisposes organs to cancer. Reversible phosphorylation mediated by protein kinases and...
关键词：蛋白磷酸酶 DNA损伤 苏氨酸 丝氨酸 反应 蛋白激酶抑制剂 可逆磷酸化 细胞活动 
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