国家自然科学基金(30525024)

作品数:1被引量:7H指数:1
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相关期刊:《Acta Pharmacologica Sinica》更多>>
相关主题:SYNTHASEMALONYL-COATRANSACYLASEJUGLONEDEHYDRATASE更多>>
相关领域:医药卫生更多>>
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Natural product juglone targets three key enzymes from Helicobacter pylori: inhibition assay with crystal structure characterization被引量:7
《Acta Pharmacologica Sinica》2008年第7期870-876,共7页Yun-hua KONG Liang ZHANG Zheng-yi YANG Cong HAN Li-hong HU Hua-liang JIANG Xu SHEN 
This work was supported by the National Natural Science Foundation of China (No 30525024, 20721003, and 90713046).
Aim: To investigate the inhibition features of the natural product juglone (5- hydroxy-1,4-naphthoquinone) against the three key enzymes from Helicobacter pylori (cystathionine γ-synthase [HpCGS], malonyl-CoA:ac...
关键词:cystathionine γ-synthase malonyl-CoA:acyl carrier protein transacylase β-hydroxyacyl-ACP dehydratase inhibitor type complex structure 
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