国家自然科学基金(39870378)

作品数：4被引量：2H指数：1
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Effects of Huangqi （Hex） on Inducing Cell Differentiation and Cell Death in K562 and HEL Cells
《中国生物学文摘》2005年第11期67-73,共7页Xiao-Dong CHENG Chun-Hui HOU Xue-Jun ZHANG Heng-Yue XIE Wei-Ying ZHOU Lei YANG Shu-Bing ZHANG Ruo-Lan QIAN 
This work was supported by the grants from tile National Natural Science Foundation of China （No. 39893320, No. 39870378） and the Foundation of the Chinese Academy of Sciences （No. K.j 982-j1618）Acknowledgements We are gratcful to Mrs. M.-Y. ZH0U for technical assistance.
关键词：细胞分化 细胞凋亡 K562 海拉细胞 
Functional Analysis of Multiple Transcription Factor Sites in a Regulatory Element of Human ε-Globin Gene
《Acta Biochimica et Biophysica Sinica》2004年第10期673-680,共8页Chun-HuiHOU JianHUANG Ruo-LanQIAN 
The work was supported by a grant from the National Natural Science Foundation of China (No. 39870378)
The developmental control of the human ε-globin gene expression is mediated by transcrip- tional regulatory elements in the 5' flanking DNA of this gene. A previously identified negative regulatory element (–3028 ...
关键词：ε-globin gene regulatory element NF-ΚB GATA 
The in vitro reconstitution of nucleosome and its binding patterns with HMG1/2 and HMG14/17 proteins被引量：2
《Cell Research》2003年第5期351-360,共10页SHUBINGZHANG JIANHUANG HUIZHAO YIZHANG CHUNHUIHOU XIAODONGCHENG CHUJIANG MINQIANLI JUNHU RUOLANQIAN 
This work was supported by the National Natural Science Foundation of China(Grant No.39893320 and 39870378);the Foundation of the Chinese Academy of Sciences(Grant No.Kj982-j1-618).
Using atomic force microscopy (AFM), the dynamic process of the in vitro nucleosome reconstitution followed by slow dilution from high salt to low salt was visualized. Data showed that the histone octamers were dissoc...
关键词：atomic force microscopy HMG proteins (HMG1/2 and HMG14/17) human β-globin gene in vitro reconstitution nucleosome. 
The interaction between the human β-globin locus control region and nuclear matrix
《Cell Research》2002年第5期411-416,共6页SHU BING ZHANG, Ruo LAN QIANState Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, China 
supported by the National Natural Science Foundation of China(Grant No.39893320 and 39870378);the Foundation of the Chinese Academy of Sciences (Grant No. KJ982-J1-618).
Our previous study showed that hydroxyurea (Hu) could induce HEL cells to express humanβ-globin gene. However the molecular mechanisms by which the expression of β-globin gene is activated and regulated are poorly u...
关键词：human β-globin LCR nuclear matrix proteins nuclear matrix HEL cells. 
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