云南高校图书馆联盟文献共享服务平台- 国家重点基础研究发展计划(2013CB733700)

国家重点基础研究发展计划(2013CB733700): 作品数：13被引量：23H指数：3; 导出分析报告; 相关作者：何业靳鹏伟朱世琴朱为宏常英军更多>>; 相关机构：华东理工大学北京大学复旦大学更多>>; 相关期刊：《Science China Chemistry》《影像科学与光化学》《中华血液学杂志》《中华器官移植杂志》更多>>; 相关主题：NEAR-INFRAREDΑ-酮戊二酸荧光探针NIR乙烯更多>>; 相关领域：理学医药卫生化学工程生物学更多>>

cNGR-based synergistic-targeted NIR fluorescent probe for tracing and bioimaging of pancreatic ductal adenocarcinoma: 《Science China Chemistry》2018年第2期184-191,共8页Yan Tang Andong Shao Jun Cao Hui Li Qiang Li Meiying Zeng Ming Liu Yingsheng Cheng Weihong Zhu; supported by the National Basic Research Program of China (2013CB733700);the National Natural Science Foundation of China for Creative Research Groups (21421004);Key Project (21636002);Distinguished Young Scholars (21325625);NSFC/China;the Oriental Scholarship;Science and Technology Commission of Shanghai Municipality (15XD1501400);the Fundamental Research Funds for the Central Universities (222201717003);Program of Introducing Talents of Discipline to Universities (B16017); Identification of fluorescent biomarkers with peptide ligand-directed receptors for diagnosis or theranostic of pancreatic ductal adenocarcinoma (PDAC) is still challenging. As potential prognostic/predictive bioimagi...; 关键词：NIR fluorescence probe NGR aminopeptidase N Caveolin-1 pancreatic ductal adenocarcinoma

基于罗丹明和BODIPY单元的FRET探针的合成及其对小分子α-酮戊二酸的检测被引量：1: 《影像科学与光化学》2017年第3期265-273,共9页何业唐俊马郭志前靳鹏伟朱世琴朱为宏; 国家973计划(2013CB733700);国家自然科学基金(21476076)资助; 小分子α-酮戊二酸(α-KA)是人体新陈代谢的一种十分重要的产物,与多种疾病存在直接或者间接的关系,可以对临床诊断提供帮助。以BODIPY单元作为能量给体、罗丹明单元作为能量受体,利用二者存在重叠的光谱,本文设计了一种基于罗丹明和BOD...; 关键词：罗丹明 BODIPY Α-酮戊二酸荧光探针

A near-infrared fluorescent probe for monitoring fluvastatin-stimulated endogenous H_2S production被引量：3: 《Chinese Chemical Letters》2017年第2期218-221,共4页Li-Li Zhang Hui-Kun Zhu Chun-Chang Zhao Xian-Feng Gu; financial support by the National Natural Science Foundation of China (Nos. 21190033, 21372083, 21572039);National 973 Program (No. 2013CB733700); Most reported fluorescent probes have limitations in practical applications in living systems due to the strong autofluorescence background,construction of probes with near-infrared（NIR） fluorescence emission is an ...; 关键词：Fluorescent probe Near-infrared fluorescence emission Endogenous H2S detection Fluvastatin

A novel o-nitrobenzyl-based photocleavable antitumor prodrug with the capability of releasing 5-fluorourail被引量：2: 《Science Bulletin》2016年第6期459-467,共9页Shuli Mo Ying Wen Fengfeng Xue Haichuang Lan Yueyuan Mao Guanglei Lv Tao Yi; supported by the National Basic Research Program of China (2013CB733700);the China National Funds for Distinguished Young Scholars (21125104);the National Natural Science Foundation of China (51373039);Specialized Research Fund for the Doctoral Program of Higher Education (20120071130008); An o-nitrobenzyl-based photocleavable antitumor prodrug with a terminal carboxyl group was designed and synthesized.The photolysis properties of the prodrug were investigated by means of1H NMR,HPLC,UV,and MTT methods....; 关键词：Antitumor prodrug 5-Fluorourail Photocleavable o-Nitrobenzyl

A novel colorimetric and ratiometric NIR fluorescent sensor for glutathione based on dicyanomethylene-4H-pyran in living cells被引量：1: 《Science China Chemistry》2016年第1期62-69,共8页xumeng wu andong shao shiqin zhu zhiqian guo weihong zhu; the National Basic Research Program(2013CB733700);the National Natural Science Foundation of China for Creative Research Groups(21421004);Distinguished Young Scholars(21325625);the Oriental Scholarship,the Fundamental Research Funds for the Central Universities(WJ1416005);Science and Technology Commission of Shanghai Municipality(15XD1501400); Glutathione(GSH)plays a critical role in maintaining oxidation-reduction homeostasis in biological systems.Considering the detection of GSH by fluorescence sensors is limited by either the short wavelength emission or...; 关键词：near-infrared GSH ratiometric colorimetric fluorescent sensor

A fast approach to optimize dye loading of photoanode via ultrasonic technique for highly efficient dye-sensitized solar cells被引量：1: 《Journal of Energy Chemistry》2015年第6期750-755,共6页Jue Chen Xing Li Wenjun Wu Jianli Hua; supported by the Science Fund for Creative Research Groups(21421004);the National Basic Research 973 Program(2013CB733700);NSFC/China(21172073,21372082,21572062 and 91233207); A distinctive method is proposed by simply utilizing ultrasonic technique in Ti02 electrode fabrication in order to improve the optoelectronic performance of dye-sensitized solar cells （DSSCs）. Dye molecules are at ...; 关键词：Ultrasonic technique Fast dye loading Photoanode High efficiency DSSC

基于罗丹明B的激活型α-酮戊二酸荧光探针被引量：2: 《影像科学与光化学》2015年第3期195-202,共8页焦长红何业靳鹏伟朱世琴朱为宏; 国家973计划(2013CB733700);国家自然科学基金(21476076)资助; α-酮戊二酸(α-KA)是人体三羧酸循环的一个重要代谢中间体,异柠檬酸脱氢酶-1(IDH1)及异柠檬酸脱氢酶-2(IDH2)的突变将导致α-KA转化为2-羟基戊二酸(2HG),该过程与急性骨髓性白血病(AML)密切相关,因此检测人体内α-KA的含量变化具有重...; 关键词：罗丹明B Α-酮戊二酸荧光探针激活型

分子探针:提速癌症诊断的新工具被引量：1: 《世界复合医学》2015年第3期207-211,共5页贺晓鹏; 国家重点基础研究发展计划(973计划)项目(2013CB733700); 癌症的快速、准确血液诊断是国际生命健康领域亟待解决的科学问题。然而,现有临床诊断技术存在操作流程繁复、技术要求高、耗时长且成本昂贵等缺陷。发展可用于快速捕捉血液癌标志物的简易、经济型诊断新工具逐渐成为国内外学术研究热...; 关键词：癌症血液标志物分子探针分子诊断荧光

Synthesis and properties of novel photochromic bisthienylethenes containing imidazole and imidazolium derivatives被引量：1: 《Chinese Chemical Letters》2014年第5期762-766,共5页Jia-Qi Zhang Qiao-Chun Wang Lei Zou Chun-Yang Jia; financially supported by National Basic Research 973 Program (No. 2013CB733700);National Natural Science Foundation of China (Nos. 21190033, 21302056 and 21072058);the Open Foundation of State Key Laboratory of Electronic Thin Films and Integrated Devices (No. KFJJ201311); A series of bisthienylethenes containing imidazole and imidazolium derivatives have been prepared and the products have been characterized by means of NMR and MS.Their photochromic and fluorescent switch properties ha...; 关键词：Photochromism Bisthienylethenes Imidazole Fluorescence

二芳乙烯荧光开关材料及其应用进展被引量：6: 《影像科学与光化学》2014年第1期28-42,共15页吕光磊刘克印孟路燕易涛; 国家973项目(2013CB733700);国家自然科学基金项目(21125104;91022021;51373039)资助; 二芳乙烯作为经典的光致变色体系,因本身具有热稳定性好、抗疲劳性强、响应时间快、量子产率高等优点,越来越受到研究者的重视。本文综述了近几年来作者课题组在光开关二芳乙烯化合物研究方面的一些进展,主要涉及二芳乙烯荧光开关材料...; 关键词：光致变色二芳乙烯生物成像荧光开关

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