supported by the National Natural Science Foundation of China(Grant Nos.30972766,31170852,81001322,81172795,and 81072622);Specialized Research Fund for the Doctoral Program of Higher Education(Grant No.20094402110004);Scientific Research Foundation of Shantou University Medical College(Grant No.LC0401);211 Project of Guangdong Province(Mechanism and Prevention of Emerging Infectious Diseases)
Non-structural protein 1 (NS1) of the influenza virus plays a crucial role in modulating the host immune response and facili- tating virus replication. The formation of a homodimer or an oligomer is necessary for NS...