Project supported by the National Natural Science Foundation of China (Grant Nos 10204013, 90103031, 10074030, 10474041, 90403120 and 10021001), and the Nonlinear Project (973) of the National Science Ministry, China.
In this work, we make an investigation on the preferences of orientations between amino acids using the orientation defined based on the local geometry of the amino acids concerned. It is found that there are common p...
the National Natural Science Foundation of China (Grant Nos. 90403120, 10474041 and 10021001);the Nonlinear Project (973) of the NSM
Sequence alignment is a common method for finding protein structurally conserved/similar regions. However, sequence alignment is often not accurate if sequence identities between to-be-aligned se- quences are less tha...
This work was supported by the National Natural Science Foundation of China(Grant Nos.90403120,10474041,10204013 and 10021001);FANEDD to Wang Jun.
The orientation between the backbone residues of proteins is defined based on the local configurations and the corresponding preferences are analyzed by statistics.It is found that all the residue pairs have some spec...
supported by the National Natural Science Foundation of China(Grant Nos.90403120,10474041,and 10021001);the Nonlinear Project(973)of the NSM.
Homology detection plays a key role in bioinformatics, whereas substitution matrix is one of the most important components in homology detec- tion. Thus, besides the improvement of alignment algorithms, another effect...
Project supported by the National Natural Science Foundation of China (Grant Nos 90103031, 10474041, 90403120 and 10021001), and the Nonlinear Project (973) of the NSM.
The folding dynamics and structural characteristics of peptides RTKAWNRQLYPEW (P1) and RTKQLYPEW (P2) are investigated by using all-atomic simulation procedure CHARMM in this work. The results show that P1, a segm...