This work was supported by Zhejiang Provincial Natural Science Foundation for Distinguished Young Scholars (LR15H190001), the National Natural Science Foundation of China (31570027), and a start-up package from Zhejiang University (Y.F.). Dr. Feng is a recipient of the "Young 1000 Talents" Award.
Polymyxin acts as an ultimate line of refuge against the severe infections by multidrug-resistant Gram- negative pathogens. This conventional idea is challenged dramatically by the recent discovery of mobile colistin ...