GOOSECOID

作品数：3被引量：2H指数：1
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相关领域：医药卫生生物学更多>>
相关作者：尹洁谢肖立姜慧卿李琳王义权更多>>
相关机构：河北医科大学第四军医大学口腔医院空军军医大学（第四军医大学）东南大学更多>>
相关期刊：《Chinese Medical Journal》《中国科技论文》《Cell Research》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金更多>>
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Oncogene goosecoid is transcriptionally regulated by E2F1 and correlates with disease progression in prostate cancer
《Chinese Medical Journal》2024年第15期1844-1856,共13页Yue Ge Sheng Ma Qiang Zhou Zezhong Xiong Yanan Wang Le Li Zheng Chao Junbiao Zhang Tengfei Li Zixi Wu Yuan Gao Guanyu Qu Zirui Xi Bo Liu Xi Wu Zhihua Wang 
supported by the National Natural Science Foundation of China(Nos.82173068,81974400);the Applied Basic Research Plan from Qinghai Provincial Department of Science and Technology(No.2021-ZJ-723).
Background:Although some well-established oncogenes are involved in cancer initiation and progression such as prostate cancer(PCa),the long tail of cancer genes remains to be defined.Goosecoid(GSC)has been implicated ...
关键词：GOOSECOID Prostate cancer Prognosis E2F transcription factor 1 Trametinib 
Cdhl regulates craniofacial development via APC- dependent ubiquitination and activation of Goosecoid被引量：2
《Cell Research》2016年第6期699-712,共14页Rui Shao Jia Liu Guang Yan Jinfang Zhang Yujiao Han Jianfeng Guo Zhan Xu Zhu Yuan Jiankang Liu Marcos Malumbres Lixin Wan Wenyi Wei Weiguo Zou 
Acknowledgments We thank Brian North, Shavali Shaik, Aletn W. Lau, Matthew B. Greenblatt, Hiroyuki Inuzuka and Pengda Liu for critical reading of the manuscript, and members of the Zou and Wei labs for useful discussions. This work was supported by the Chinese Ministry of Science and Technology （MOST, 973 Program; 2014CB964704 and 2015CB964503）, the National Natural Science Foundation of China （NSFC; 31371463） and NIH （GM089763, GM094777 and CA177910 to WW）. WZ is a scholar of the ＇National I000 Young Talents Program of China＇ and ＇the National Science Fund for Excellent Young Scholars＇ （NSFC; 81322027）. WW is a Leukemia and Lymphoma Society Scholar and ACS Research Scholar.
Craniofacial anomalies （CFAs） characterized by birth defects of skull and facial bones are the most frequent congenital disease. Genomic analysis has identified multiple genes responsible for CFAs; however, the unde...
关键词：APC Cdhl Wwp2 GOOSECOID Sox6 craniofacial development craniofacial anomalies 
文昌鱼胚胎发育过程中Goosecoid基因的表达分析
《中国科技论文》2016年第6期624-627,共4页商留珂 李光 王义权 
高等学校博士学科点专项科研基金资助项目(20110121120002);国家自然科学基金资助项目(31372188;31101631)
为更详细地了解Goosecoid(Gsc)基因在文昌鱼中的表达情况,研究通过实时荧光定量PCR(real-time quantitative polymerase chain reaction,RT-qPCR)和整胚原位杂交(whole mount in situ hybridization,WISH)对Gsc基因在白氏文昌鱼不同发...
关键词：发育生物学 文昌鱼 胚胎发育 Gsc基因 基因表达谱 
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